Bruce Bean, PhD
Robert Winthrop Professor of Neurobiology, Harvard Medical School
Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.
Lacosamide Inhibition of Nav1.7 Voltage-Gated Sodium Channels: Slow Binding to Fast-Inactivated States.
Modulation of neuronal sodium channels by the sea anemone peptide BDS-I.
State-dependent enhancement of subthreshold A-type potassium current by 4-aminopyridine in tuberomammillary nucleus neurons.
Potassium currents during the action potential of hippocampal CA3 neurons.
Alteration of P-type calcium channel gating by the spider toxin omega-Aga-IVA.
A new Conus peptide ligand for mammalian presynaptic Ca2+ channels.
Authors: Authors: Hillyard DR, Monje VD, Mintz IM, Bean BP, Nadasdi L, Ramachandran J, Miljanich G, Azimi-Zoonooz A, McIntosh JM, Cruz LJ, et al.
Neuron
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Neuron
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Multiple types of calcium channels in heart muscle and neurons. Modulation by drugs and neurotransmitters.
Cooperative regulation by G proteins and Na(+) of neuronal GIRK2 K(+) channels.
Authors: Authors: Wang W, Touhara KK, Weir K, Bean BP, MacKinnon R.
Elife
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Elife
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Targeting of sodium channel blockers into nociceptors to produce long-duration analgesia: a systematic study and review.
Authors: Authors: Roberson DP, Binshtok AM, Blasl F, Bean BP, Woolf CJ.
Br J Pharmacol
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Br J Pharmacol
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Neurophysiology: stressful pacemaking.