Isaac Chiu, PhD

Assistant Professor of Immunology, Harvard Medical School
Neuro-immune interactions in inflammation and host defense: Implications for transplantation.
Authors: Authors: Chavan SS, Ma P, Chiu IM.
Am J Transplant
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Bacteria activate sensory neurons that modulate pain and inflammation.
Authors: Authors: Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ.
Nature
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The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.
Authors: Authors: Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.
Nature
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A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model.
Authors: Authors: Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S, Myers RM, Maniatis T.
Cell Rep
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Neuro-immune interactions in allergic diseases: novel targets for therapeutics.
Authors: Authors: Voisin T, Bouvier A, Chiu IM.
Int Immunol
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Neurogenic inflammation and the peripheral nervous system in host defense and immunopathology.
Authors: Authors: Chiu IM, von Hehn CA, Woolf CJ.
Nat Neurosci
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An Intestinal Organ Culture System Uncovers a Role for the Nervous System in Microbe-Immune Crosstalk.
Authors: Authors: Yissachar N, Zhou Y, Ung L, Lai NY, Mohan JF, Ehrlicher A, Weitz DA, Kasper DL, Chiu IM, Mathis D, Benoist C.
Cell
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Blockade of self-reactive IgM significantly reduces injury in a murine model of acute myocardial infarction.
Authors: Authors: Haas MS, Alicot EM, Schuerpf F, Chiu I, Li J, Moore FD, Carroll MC.
Cardiovasc Res
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Nociceptor nerves set the stage for skin immunity.
Authors: Authors: Pinho-Ribeiro FA, Chiu IM.
Cell Res
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Sensory neuron regulation of gastrointestinal inflammation and bacterial host defence.
Authors: Authors: Lai NY, Mills K, Chiu IM.
J Intern Med
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