John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Duplication and amplification of toxin genes in Vibrio cholerae.
Authors: Authors: Mekalanos JJ.
Cell
View full abstract on Pubmed
Sensing of intracellular Hcp levels controls T6SS expression in Vibrio cholerae.
Authors: Authors: Manera K, Caro F, Li H, Pei TT, Hersch SJ, Mekalanos JJ, Dong TG.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Bacterial cGAS-like enzymes synthesize diverse nucleotide signals.
Authors: Authors: Whiteley AT, Eaglesham JB, de Oliveira Mann CC, Morehouse BR, Lowey B, Nieminen EA, Danilchanka O, King DS, Lee ASY, Mekalanos JJ, Kranzusch PJ.
Nature
View full abstract on Pubmed
Fitness cost of antibiotic susceptibility during bacterial infection.
Authors: Authors: Roux D, Danilchanka O, Guillard T, Cattoir V, Aschard H, Fu Y, Angoulvant F, Messika J, Ricard JD, Mekalanos JJ, Lory S, Pier GB, Skurnik D.
Sci Transl Med
View full abstract on Pubmed
Vaccine economics: what price human life?
Authors: Authors: Mekalanos JJ.
Sci Transl Med
View full abstract on Pubmed
Sigma E regulators control hemolytic activity and virulence in a shrimp pathogenic Vibrio harveyi.
Authors: Authors: Rattanama P, Thompson JR, Kongkerd N, Srinitiwarawong K, Vuddhakul V, Mekalanos JJ.
PLoS One
View full abstract on Pubmed
Quorum-regulated biofilms enhance the development of conditionally viable, environmental Vibrio cholerae.
Authors: Authors: Kamruzzaman M, Udden SM, Cameron DE, Calderwood SB, Nair GB, Mekalanos JJ, Faruque SM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
A type III secretion system in Vibrio cholerae translocates a formin/spire hybrid-like actin nucleator to promote intestinal colonization.
Authors: Authors: Tam VC, Serruto D, Dziejman M, Brieher W, Mekalanos JJ.

View full abstract on Pubmed
Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization.
Authors: Authors: Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ.
Science
View full abstract on Pubmed
Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area.
Authors: Authors: Faruque SM, Chowdhury N, Kamruzzaman M, Dziejman M, Rahman MH, Sack DA, Nair GB, Mekalanos JJ.
Proc Natl Acad Sci U S A
View full abstract on Pubmed