Vidyasiri Vemulapalli, PhD

Research Fellow in Biological Chemistry and Molecular Pharmacology (EXT), Dana-Farber Cancer Institute
Structural reorganization of SHP2 by oncogenic mutations and implications for oncoprotein resistance to allosteric inhibition.
Authors: Authors: LaRochelle JR, Fodor M, Vemulapalli V, Mohseni M, Wang P, Stams T, LaMarche MJ, Chopra R, Acker MG, Blacklow SC.
Nat Commun
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CARM1 methylates MED12 to regulate its RNA-binding ability.
Authors: Authors: Cheng D, Vemulapalli V, Lu Y, Shen J, Aoyagi S, Fry CJ, Yang Y, Foulds CE, Stossi F, Treviño LS, Mancini MA, O'Malley BW, Walker CL, Boyer TG, Bedford MT.
Life Sci Alliance
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Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9.
Authors: Authors: Hamidi T, Singh AK, Veland N, Vemulapalli V, Chen J, Hardikar S, Bao J, Fry CJ, Yang V, Lee KA, Guo A, Arrowsmith CH, Bedford MT, Chen T.
J Biol Chem
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Identification of an allosteric benzothiazolopyrimidone inhibitor of the oncogenic protein tyrosine phosphatase SHP2.
Authors: Authors: LaRochelle JR, Fodor M, Ellegast JM, Liu X, Vemulapalli V, Mohseni M, Stams T, Buhrlage SJ, Stegmaier K, LaMarche MJ, Acker MG, Blacklow SC.
Bioorg Med Chem
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Using oriented peptide array libraries to evaluate methylarginine-specific antibodies and arginine methyltransferase substrate motifs.
Authors: Authors: Gayatri S, Cowles MW, Vemulapalli V, Cheng D, Sun ZW, Bedford MT.
Sci Rep
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Adaptor protein GRB2 promotes Src tyrosine kinase activation and podosomal organization by protein-tyrosine phosphatase ? in osteoclasts.
Authors: Authors: Levy-Apter E, Finkelshtein E, Vemulapalli V, Li SS, Bedford MT, Elson A.
J Biol Chem
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Immunoaffinity enrichment and mass spectrometry analysis of protein methylation.
Authors: Authors: Guo A, Gu H, Zhou J, Mulhern D, Wang Y, Lee KA, Yang V, Aguiar M, Kornhauser J, Jia X, Ren J, Beausoleil SA, Silva JC, Vemulapalli V, Bedford MT, Comb MJ.
Mol Cell Proteomics
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Loss of the major Type I arginine methyltransferase PRMT1 causes substrate scavenging by other PRMTs.
Authors: Authors: Dhar S, Vemulapalli V, Patananan AN, Huang GL, Di Lorenzo A, Richard S, Comb MJ, Guo A, Clarke SG, Bedford MT.
Sci Rep
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Methods applied to the study of protein arginine methylation.
Authors: Authors: Cheng D, Vemulapalli V, Bedford MT.
Methods Enzymol
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Loss of the methyl lysine effector protein PHF20 impacts the expression of genes regulated by the lysine acetyltransferase MOF.
Authors: Authors: Badeaux AI, Yang Y, Cardenas K, Vemulapalli V, Chen K, Kusewitt D, Richie E, Li W, Bedford MT.
J Biol Chem
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