Zuzana Tothova, MD, PhD

Assistant Professor of Medicine, Dana-Farber Cancer Institute
Intergenerational epigenetic inheritance of cancer susceptibility in mammals.
Authors: Authors: Lesch BJ, Tothova Z, Morgan EA, Liao Z, Bronson RT, Ebert BL, Page DC.
Elife
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FoxO transcription factors and stem cell homeostasis: insights from the hematopoietic system.
Authors: Authors: Tothova Z, Gilliland DG.
Cell Stem Cell
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Multiplex CRISPR/Cas9-Based Genome Editing in Human Hematopoietic Stem Cells Models Clonal Hematopoiesis and Myeloid Neoplasia.
Authors: Authors: Tothova Z, Krill-Burger JM, Popova KD, Landers CC, Sievers QL, Yudovich D, Belizaire R, Aster JC, Morgan EA, Tsherniak A, Ebert BL.
Cell Stem Cell
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[FoxO: stress or eternal life].
Authors: Authors: Tothova Z, Mercher T.
Med Sci (Paris)
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Doubling Down on Mutant RAS Can MEK or Break Leukemia.
Authors: Authors: Tothova Z, Ebert BL.
Cell
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The retinoblastoma binding protein RBP2 is an H3K4 demethylase.
Authors: Authors: Klose RJ, Yan Q, Tothova Z, Yamane K, Erdjument-Bromage H, Tempst P, Gilliland DG, Zhang Y, Kaelin WG.
Cell
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Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML.
Authors: Authors: Puram RV, Kowalczyk MS, de Boer CG, Schneider RK, Miller PG, McConkey M, Tothova Z, Tejero H, Heckl D, Järås M, Chen MC, Li H, Tamayo A, Cowley GS, Rozenblatt-Rosen O, Al-Shahrour F, Regev A, Ebert BL.
Cell
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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis.
Authors: Authors: Paik JH, Kollipara R, Chu G, Ji H, Xiao Y, Ding Z, Miao L, Tothova Z, Horner JW, Carrasco DR, Jiang S, Gilliland DG, Chin L, Wong WH, Castrillon DH, DePinho RA.
Cell
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Mutant Calreticulin Requires Both Its Mutant C-terminus and the Thrombopoietin Receptor for Oncogenic Transformation.
Authors: Authors: Elf S, Abdelfattah NS, Chen E, Perales-Patón J, Rosen EA, Ko A, Peisker F, Florescu N, Giannini S, Wolach O, Morgan EA, Tothova Z, Losman JA, Schneider RK, Al-Shahrour F, Mullally A.
Cancer Discov
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FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.
Authors: Authors: Tothova Z, Kollipara R, Huntly BJ, Lee BH, Castrillon DH, Cullen DE, McDowell EP, Lazo-Kallanian S, Williams IR, Sears C, Armstrong SA, Passegué E, DePinho RA, Gilliland DG.
Cell
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