Allon Klein, PhD
Associate Professor of Systems Biology, Harvard Medical School
Epidermal Tissue Adapts to Restrain Progenitors Carrying Clonal p53 Mutations.
Authors: Authors: Murai K, Skrupskelyte G, Piedrafita G, Hall M, Kostiou V, Ong SH, Nagy T, Cagan A, Goulding D, Klein AM, Hall BA, Jones PH.
Cell Stem Cell
View full abstract on Pubmed
Cell Stem Cell
View full abstract on Pubmed
InDrops and Drop-seq technologies for single-cell sequencing.
Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells.
Authors: Authors: Snippert HJ, van der Flier LG, Sato T, van Es JH, van den Born M, Kroon-Veenboer C, Barker N, Klein AM, van Rheenen J, Simons BD, Clevers H.
Cell
View full abstract on Pubmed
Cell
View full abstract on Pubmed
Molecular diversification of regulatory T cells in nonlymphoid tissues.
Authors: Authors: DiSpirito JR, Zemmour D, Ramanan D, Cho J, Zilionis R, Klein AM, Benoist C, Mathis D.
Sci Immunol
View full abstract on Pubmed
Sci Immunol
View full abstract on Pubmed
Genetic screening enters the single-cell era.
Intestinal stem cell replacement follows a pattern of neutral drift.
Authors: Authors: Lopez-Garcia C, Klein AM, Simons BD, Winton DJ.
Science
View full abstract on Pubmed
Science
View full abstract on Pubmed
A single-cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte.
Authors: Authors: Plasschaert LW, Žilionis R, Choo-Wing R, Savova V, Knehr J, Roma G, Klein AM, Jaffe AB.
Nature
View full abstract on Pubmed
Nature
View full abstract on Pubmed
Single-cell barcoding and sequencing using droplet microfluidics.
Authors: Authors: Zilionis R, Nainys J, Veres A, Savova V, Zemmour D, Klein AM, Mazutis L.
Nat Protoc
View full abstract on Pubmed
Nat Protoc
View full abstract on Pubmed
Mouse germ line stem cells undergo rapid and stochastic turnover.
Authors: Authors: Klein AM, Nakagawa T, Ichikawa R, Yoshida S, Simons BD.
Cell Stem Cell
View full abstract on Pubmed
Cell Stem Cell
View full abstract on Pubmed
Technique to measure the expression dynamics of each gene in a single cell.