Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Potent induction of FucT-VII in activated CD4+ T cells by TGF-b1 through a p38 MAP kinase-dependent pathway
Authors: Authors: Wagers AJ, Kansas GS
Journal of Immunology
Attenuation of PKCd enhances metabolic activity and promotes expansion of blood progenitors.
Authors: Authors: Rao TN, Gupta MK, Softic S, Wang LD, Jang YC, Thomou T, Bezy O, Kulkarni RN, Kahn CR, Wagers AJ.
EMBO J
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EGLN1 Inhibition and Rerouting of a-Ketoglutarate Suffice for Remote Ischemic Protection.
Authors: Authors: Olenchock BA, Moslehi J, Baik AH, Davidson SM, Williams J, Gibson WJ, Chakraborty AA, Pierce KA, Miller CM, Hanse EA, Kelekar A, Sullivan LB, Wagers AJ, Clish CB, Vander Heiden MG, Kaelin WG.
Cell
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Young, proliferative thymic epithelial cells engraft and function in aging thymuses.
Authors: Authors: Kim MJ, Miller CM, Shadrach JL, Wagers AJ, Serwold T.
J Immunol
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Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle.
Authors: Authors: Sinha M, Jang YC, Oh J, Khong D, Wu EY, Manohar R, Miller C, Regalado SG, Loffredo FS, Pancoast JR, Hirshman MF, Lebowitz J, Shadrach JL, Cerletti M, Kim MJ, Serwold T, Goodyear LJ, Rosner B, Lee RT, Wagers AJ.
Science
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Growth differentiation factor 11 is a circulating factor that reverses age-related cardiac hypertrophy.
Authors: Authors: Loffredo FS, Steinhauser ML, Jay SM, Gannon J, Pancoast JR, Yalamanchi P, Sinha M, Dall'Osso C, Khong D, Shadrach JL, Miller CM, Singer BS, Stewart A, Psychogios N, Gerszten RE, Hartigan AJ, Kim MJ, Serwold T, Wagers AJ, Lee RT.
Cell
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Rejuvenation of regeneration in the aging central nervous system.
Authors: Authors: Ruckh JM, Zhao JW, Shadrach JL, van Wijngaarden P, Rao TN, Wagers AJ, Franklin RJ.
Cell Stem Cell
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Systemic signals regulate ageing and rejuvenation of blood stem cell niches.
Authors: Authors: Mayack SR, Shadrach JL, Kim FS, Wagers AJ.
Nature
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Wnt not, waste not.
Authors: Authors: Wagers AJ.
Cell Stem Cell
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Hematopoietic stem cells give rise to perivascular endothelial-like cells during brain tumor angiogenesis.
Authors: Authors: Udani VM, Santarelli JG, Yung YC, Wagers AJ, Cheshier SH, Weissman IL, Tse V.
Stem Cells Dev
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