Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Direct Reprogramming of Mouse Fibroblasts into Functional Skeletal Muscle Progenitors.
Authors: Authors: Bar-Nur O, Gerli MFM, Di Stefano B, Almada AE, Galvin A, Coffey A, Huebner AJ, Feige P, Verheul C, Cheung P, Payzin-Dogru D, Paisant S, Anselmo A, Sadreyev RI, Ott HC, Tajbakhsh S, Rudnicki MA, Wagers AJ, Hochedlinger K.
Stem Cell Reports
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Molecular circuitry of stem cell fate in skeletal muscle regeneration, ageing and disease.
Authors: Authors: Almada AE, Wagers AJ.
Nat Rev Mol Cell Biol
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Myogenic tumors in nevoid Basal cell carcinoma syndrome.
Authors: Authors: Hettmer S, Teot LA, Kozakewich H, Werger AM, Davies KJ, Fletcher CD, Grier HE, Rodriguez-Galindo C, Wagers AJ.
J Pediatr Hematol Oncol
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Lung stem cell differentiation in mice directed by endothelial cells via a BMP4-NFATc1-thrombospondin-1 axis.
Authors: Authors: Lee JH, Bhang DH, Beede A, Huang TL, Stripp BR, Bloch KD, Wagers AJ, Tseng YH, Ryeom S, Kim CF.
Cell
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Identification of transcriptional regulators in the mouse immune system.
Authors: Authors: Jojic V, Shay T, Sylvia K, Zuk O, Sun X, Kang J, Regev A, Koller D, Best AJ, Knell J, Goldrath A, Joic V, Koller D, Shay T, Regev A, Cohen N, Brennan P, Brenner M, Kim F, Rao TN, Wagers A, Heng T, Ericson J, Rothamel K, Ortiz-Lopez A, Mathis D, Benoist C, Bezman NA, Sun JC, Min-Oo G, Kim CC, Lanier LL, Miller J, Brown B, Merad M, Gautier EL, Jakubzick C, Randolph GJ, Monach P, Blair DA, Dustin ML, Shinton SA, Hardy RR, Laidlaw D, Collins J, Gazit R, Rossi DJ, Malhotra N, Sylvia K, Kang J, Kreslavsky T, Fletcher A, Elpek K, Bellemarte-Pelletier A, Malhotra D, Turley S.
Nat Immunol
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Efficient generation of iPS cells from skeletal muscle stem cells.
Authors: Authors: Tan KY, Eminli S, Hettmer S, Hochedlinger K, Wagers AJ.
PLoS One
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BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells.
Authors: Authors: Schemionek M, Elling C, Steidl U, Bäumer N, Hamilton A, Spieker T, Göthert JR, Stehling M, Wagers A, Huettner CS, Tenen DG, Tickenbrock L, Berdel WE, Serve H, Holyoake TL, Müller-Tidow C, Koschmieder S.
Blood
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Immunosurveillance by hematopoietic progenitor cells trafficking through blood, lymph, and peripheral tissues.
Authors: Authors: Massberg S, Schaerli P, Knezevic-Maramica I, Köllnberger M, Tubo N, Moseman EA, Huff IV, Junt T, Wagers AJ, Mazo IB, von Andrian UH.
Cell
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Simple and efficient isolation of hematopoietic stem cells from H2K-zFP transgenic mice.
Authors: Authors: Surdez D, Kunz B, Wagers AJ, Weissman IL, Terskikh AV.
Stem Cells
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Shifting Foci of Hematopoiesis during Reconstitution by Single Stem Cells
Authors: Authors: Cao Y*, Wagers AJ*, Beilhack A, Dusich J, Bachmann MH, Negrin RS, Weissman IL, Contag CH
*Equal contributors
Proceedings of the National Academy of Science USA