Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Excessive Cellular Proliferation Negatively Impacts Reprogramming Efficiency of Human Fibroblasts.
Authors: Authors: Gupta MK, Teo AK, Rao TN, Bhatt S, Kleinridders A, Shirakawa J, Takatani T, Hu J, De Jesus DF, Windmueller R, Wagers AJ, Kulkarni RN.
Stem Cells Transl Med
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The Hippo transducer YAP1 transforms activated satellite cells and is a potent effector of embryonal rhabdomyosarcoma formation.
Authors: Authors: Tremblay AM, Missiaglia E, Galli GG, Hettmer S, Urcia R, Carrara M, Judson RN, Thway K, Nadal G, Selfe JL, Murray G, Calogero RA, De Bari C, Zammit PS, Delorenzi M, Wagers AJ, Shipley J, Wackerhage H, Camargo FD.
Cancer Cell
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Mutations in Hedgehog pathway genes in fetal rhabdomyomas.
Authors: Authors: Hettmer S, Teot LA, van Hummelen P, MacConaill L, Bronson RT, Dall'Osso C, Mao J, McMahon AP, Gruber PJ, Grier HE, Rodriguez-Galindo C, Fletcher CD, Wagers AJ.
J Pathol
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Myocardial infarction triggers chronic cardiac autoimmunity in type 1 diabetes.
Authors: Authors: Gottumukkala RV, Lv H, Cornivelli L, Wagers AJ, Kwong RY, Bronson R, Stewart GC, Schulze PC, Chutkow W, Wolpert HA, Lee RT, Lipes MA.
Sci Transl Med
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Pax3 induces differentiation of juvenile skeletal muscle stem cells without transcriptional upregulation of canonical myogenic regulatory factors.
Authors: Authors: Young AP, Wagers AJ.
J Cell Sci
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Heme oxygenase-1 deficiency leads to disrupted response to acute stress in stem cells and progenitors.
Authors: Authors: Cao YA, Wagers AJ, Karsunky H, Zhao H, Reeves R, Wong RJ, Stevenson DK, Weissman IL, Contag CH.
Blood
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Harnessing the potential of myogenic satellite cells.
Authors: Authors: Sherwood RI, Wagers AJ.
Trends Mol Med
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Isolation of adult mouse myogenic progenitors: functional heterogeneity of cells within and engrafting skeletal muscle.
Authors: Authors: Sherwood RI, Christensen JL, Conboy IM, Conboy MJ, Rando TA, Weissman IL, Wagers AJ.
Cell
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Highly enriched hematopoietic stem cells are uniquely selective in their migratory response to chemokines
Authors: Authors: Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL
Journal of Experimental Medicine
Lethal granuloma of the midline facial tissues; granuloma gangraenescens.
Authors: Authors: BRECKENRIDGE RL, WAGERS AJ, BALTZELL WH.
Ann Otol Rhinol Laryngol
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