Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair.
Authors: Authors: Woo M, Isganaitis E, Cerletti M, Fitzpatrick C, Wagers AJ, Jimenez-Chillaron J, Patti ME.
Stem Cells Dev
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Improved cutaneous healing in diabetic mice exposed to healthy peripheral circulation.
Authors: Authors: Pietramaggiori G, Scherer SS, Alperovich M, Chen B, Orgill DP, Wagers AJ.
J Invest Dermatol
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Identification of a radio-resistant and cycling dermal dendritic cell population in mice and men.
Authors: Authors: Bogunovic M, Ginhoux F, Wagers A, Loubeau M, Isola LM, Lubrano L, Najfeld V, Phelps RG, Grosskreutz C, Scigliano E, Frenette PS, Merad M.
J Exp Med
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Preuss Resident Research Award: bone marrow-derived Flk-1-expressing CD34+ cells contribute to the endothelium of tumor vessels in mouse brain.
Authors: Authors: Santarelli JG, Udani V, Yung CY, Cheshier S, Wagers A, Brekken RA, Weissman I, Tse V.
Clin Neurosurg
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Hematopoietic stem cells are uniquely selective in their migratory response to chemokines.
Authors: Authors: Wright DE, Bowman EP, Wagers AJ, Butcher EC, Weissman IL.
J Exp Med
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Expression of leukocyte fucosyltransferases regulates binding to E-selectin: relationship to previously implicated carbohydrate epitopes.
Authors: Authors: Wagers AJ, Stoolman LM, Kannagi R, Craig R, Kansas GS.
J Immunol
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Steady-state and regenerative hematopoiesis occurs normally in mice in the absence of GDF11.
Authors: Authors: Goldstein JM, Sengul H, Messemer KA, Fernández-Alfara M, Garbern JC, Kristl AC, Lee RT, Wagers AJ.
Blood
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Age-associated NF-?B signaling in myofibers alters the satellite cell niche and re-strains muscle stem cell function.
Authors: Authors: Oh J, Sinha I, Tan KY, Rosner B, Dreyfuss JM, Gjata O, Tran P, Shoelson SE, Wagers AJ.
Aging (Albany NY)
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Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.
Authors: Authors: Poggioli T, Vujic A, Yang P, Macias-Trevino C, Uygur A, Loffredo FS, Pancoast JR, Cho M, Goldstein J, Tandias RM, Gonzalez E, Walker RG, Thompson TB, Wagers AJ, Fong YW, Lee RT.
Circ Res
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Variation and genetic control of gene expression in primary immunocytes across inbred mouse strains.
Authors: Authors: Mostafavi S, Ortiz-Lopez A, Bogue MA, Hattori K, Pop C, Koller D, Mathis D, Benoist C.
J Immunol
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