Amy Wagers

Amy Wagers, PhD

Forst Family Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences, Harvard University

Dr. Amy Wagers is a Harvard College Professor and the Forst Family Professor and Co-Chair of the Department of Stem Cell and Regenerative Biology at Harvard University. She is also a Principal Faculty member of the Harvard Stem Cell Institute, a Senior Investigator in the Section on Islet Cell and Regenerative Biology at the Joslin Diabetes Center and a member of the Paul F. Glenn Center for the Biology of Aging at Harvard Medical School.  Dr. Wagers’ laboratory investigates how changes in stem cell activity impact tissue homeostasis and repair throughout life, and how stem cells may be harnessed for regenerative medicine using cell transplantation and gene editing approaches.

Rhabdomyosarcoma: current challenges and their implications for developing therapies.
Authors: Authors: Hettmer S, Li Z, Billin AN, Barr FG, Cornelison DD, Ehrlich AR, Guttridge DC, Hayes-Jordan A, Helman LJ, Houghton PJ, Khan J, Langenau DM, Linardic CM, Pal R, Partridge TA, Pavlath GK, Rota R, Schäfer BW, Shipley J, Stillman B, Wexler LH, Wagers AJ, Keller C.
Cold Spring Harb Perspect Med
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Anaplastic rhabdomyosarcoma in TP53 germline mutation carriers.
Authors: Authors: Hettmer S, Archer NM, Somers GR, Novokmet A, Wagers AJ, Diller L, Rodriguez-Galindo C, Teot LA, Malkin D.
Cancer
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Liver-derived systemic factors drive ß cell hyperplasia in insulin-resistant states.
Authors: Authors: El Ouaamari A, Kawamori D, Dirice E, Liew CW, Shadrach JL, Hu J, Katsuta H, Hollister-Lock J, Qian WJ, Wagers AJ, Kulkarni RN.
Cell Rep
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Use of cellular context to determine sarcoma phenotype in a new mouse sarcoma model.
Authors: Authors: Hettmer S, Liu J, Miller CM, Bronson RT, Langenau DM, Wagers AJ.
J Clin Oncol
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Id3 is a direct transcriptional target of Pax7 in quiescent satellite cells.
Authors: Authors: Kumar D, Shadrach JL, Wagers AJ, Lassar AB.
Mol Biol Cell
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Circulating C3 is necessary and sufficient for autoantibody-mediated arthritis
Authors: Authors: Monach PA, Verschoor A, Jacobs JP, Carroll MC, Wagers AJ, Benoist C, Mathis D
Arthritis & Rheumatism
Rejuvenation of aged progenitor cells by exposure to a young systemic environment.
Authors: Authors: Conboy IM, Conboy MJ, Wagers AJ, Girma ER, Weissman IL, Rando TA.
Nature
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Little evidence for developmental plasticity of adult hematopoietic stem cells.
Authors: Authors: Wagers AJ, Sherwood RI, Christensen JL, Weissman IL.
Science
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An sLex-deficient variant of HL60 Cells exhibits high levels of adhesion to vascular selectins: further evidence that HECA-452 and CSLEX1 monoclonal antibody epitopes are not essential for high avidity binding to vascular selectins
Authors: Authors: Wagers AJ, Stoolman LM, Craig R, Knibbs RN, Kansas GS
Journal of Immunology
Variation in zygotic CRISPR/Cas9 gene editing outcomes generates novel reporter and deletion alleles at the Gdf11 locus.
Authors: Authors: Goldstein JM, Valido A, Lewandowski JP, Walker RG, Mills MJ, Messemer KA, Besseling P, Lee KH, Wattrus SJ, Cho M, Lee RT, Wagers AJ.
Sci Rep
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