Artur Indzhykulian, PhD

Assistant Professor of Otolaryngology Head and Neck Surgery, Massachusetts Eye and Ear Infirmary
Rescue of Hearing by Gene Delivery to Inner-Ear Hair Cells Using Exosome-Associated AAV.
Authors: Authors: György B, Sage C, Indzhykulian AA, Scheffer DI, Brisson AR, Tan S, Wu X, Volak A, Mu D, Tamvakologos PI, Li Y, Fitzpatrick Z, Ericsson M, Breakefield XO, Corey DP, Maguire CA.
Mol Ther
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Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.
Authors: Authors: Vogl C, Panou I, Yamanbaeva G, Wichmann C, Mangosing SJ, Vilardi F, Indzhykulian AA, Pangršic T, Santarelli R, Rodriguez-Ballesteros M, Weber T, Jung S, Cardenas E, Wu X, Wojcik SM, Kwan KY, Del Castillo I, Schwappach B, Strenzke N, Corey DP, Lin SY, Moser T.
EMBO J
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Hair-Cell Mechanotransduction Persists in TRP Channel Knockout Mice.
Authors: Authors: Wu X, Indzhykulian AA, Niksch PD, Webber RM, Garcia-Gonzalez M, Watnick T, Zhou J, Vollrath MA, Corey DP.
PLoS One
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Primary cilia are not calcium-responsive mechanosensors.
Authors: Authors: Delling M, Indzhykulian AA, Liu X, Li Y, Xie T, Corey DP, Clapham DE.
Nature
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In the Right Place at the Right Time: Is TMC1/2 the Transduction Channel for Hearing?
Authors: Authors: Indzhykulian AA, Corey DP.
Cell Rep
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The 133-kDa N-terminal domain enables myosin 15 to maintain mechanotransducing stereocilia and is essential for hearing.
Authors: Authors: Fang Q, Indzhykulian AA, Mustapha M, Riordan GP, Dolan DF, Friedman TB, Belyantseva IA, Frolenkov GI, Camper SA, Bird JE.
Elife
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XIRP2, an actin-binding protein essential for inner ear hair-cell stereocilia.
Authors: Authors: Scheffer DI, Zhang DS, Shen J, Indzhykulian A, Karavitaki KD, Xu YJ, Wang Q, Lin JJ, Chen ZY, Corey DP.
Cell Rep
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Molecular remodeling of tip links underlies mechanosensory regeneration in auditory hair cells.
Authors: Authors: Indzhykulian AA, Stepanyan R, Nelina A, Spinelli KJ, Ahmed ZM, Belyantseva IA, Friedman TB, Barr-Gillespie PG, Frolenkov GI.
PLoS Biol
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Alterations of the CIB2 calcium- and integrin-binding protein cause Usher syndrome type 1J and nonsyndromic deafness DFNB48.
Authors: Authors: Riazuddin S, Belyantseva IA, Giese AP, Lee K, Indzhykulian AA, Nandamuri SP, Yousaf R, Sinha GP, Lee S, Terrell D, Hegde RS, Ali RA, Anwar S, Andrade-Elizondo PB, Sirmaci A, Parise LV, Basit S, Wali A, Ayub M, Ansar M, Ahmad W, Khan SN, Akram J, Tekin M, Riazuddin S, Cook T, Buschbeck EK, Frolenkov GI, Leal SM, Friedman TB, Ahmed ZM.
Nat Genet
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TRPA1-mediated accumulation of aminoglycosides in mouse cochlear outer hair cells.
Authors: Authors: Stepanyan RS, Indzhykulian AA, Vélez-Ortega AC, Boger ET, Steyger PS, Friedman TB, Frolenkov GI.
J Assoc Res Otolaryngol
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