Bing Chen, PhD

Associate Professor of Pediatrics, Boston Children's Hospital
HIV-1 envelope trimer elicits more potent neutralizing antibody responses than monomeric gp120.
Authors: Authors: Kovacs JM, Nkolola JP, Peng H, Cheung A, Perry J, Miller CA, Seaman MS, Barouch DH, Chen B.
Proc Natl Acad Sci U S A
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Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody.
Authors: Authors: Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B.
Structure
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Distinct conformational states of HIV-1 gp41 are recognized by neutralizing and non-neutralizing antibodies.
Authors: Authors: Frey G, Chen J, Rits-Volloch S, Freeman MM, Zolla-Pazner S, Chen B.
Nat Struct Mol Biol
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Role of HIV membrane in neutralization by two broadly neutralizing antibodies.
Authors: Authors: Alam SM, Morelli M, Dennison SM, Liao HX, Zhang R, Xia SM, Rits-Volloch S, Sun L, Harrison SC, Haynes BF, Chen B.
Proc Natl Acad Sci U S A
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A fusion-intermediate state of HIV-1 gp41 targeted by broadly neutralizing antibodies.
Authors: Authors: Frey G, Peng H, Rits-Volloch S, Morelli M, Cheng Y, Chen B.
Proc Natl Acad Sci U S A
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Molecular Mechanism of HIV-1 Entry.
Authors: Authors: Chen B.
Trends Microbiol
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Structural basis of coreceptor recognition by HIV-1 envelope spike.
Authors: Authors: Shaik MM, Peng H, Lu J, Rits-Volloch S, Xu C, Liao M, Chen B.
Nature
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Structure of the membrane proximal external region of HIV-1 envelope glycoprotein.
Authors: Authors: Fu Q, Shaik MM, Cai Y, Ghantous F, Piai A, Peng H, Rits-Volloch S, Liu Z, Harrison SC, Seaman MS, Chen B, Chou JJ.
Proc Natl Acad Sci U S A
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Conformational States of a Soluble, Uncleaved HIV-1 Envelope Trimer.
Authors: Authors: Liu Y, Pan J, Cai Y, Grigorieff N, Harrison SC, Chen B.
J Virol
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Antigenicity-defined conformations of an extremely neutralization-resistant HIV-1 envelope spike.
Authors: Authors: Cai Y, Karaca-Griffin S, Chen J, Tian S, Fredette N, Linton CE, Rits-Volloch S, Lu J, Wagh K, Theiler J, Korber B, Seaman MS, Harrison SC, Carfi A, Chen B.
Proc Natl Acad Sci U S A
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