Bruce Bean

Bruce Bean, PhD

Robert Winthrop Professor of Neurobiology, Harvard Medical School

Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.

Calcium channels in muscle cells isolated from rat mesenteric arteries: modulation by dihydropyridine drugs.
Authors: Authors: Bean BP, Sturek M, Puga A, Hermsmeyer K.
Circ Res
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Inhibition of A-type potassium current by the peptide toxin SNX-482.
Authors: Authors: Kimm T, Bean BP.
J Neurosci
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Pacemaking in dopaminergic ventral tegmental area neurons: depolarizing drive from background and voltage-dependent sodium conductances.
Authors: Authors: Khaliq ZM, Bean BP.
J Neurosci
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Robustness of burst firing in dissociated purkinje neurons with acute or long-term reductions in sodium conductance.
Authors: Authors: Swensen AM, Bean BP.
J Neurosci
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Properties of sodium currents and action potential firing in isolated cerebellar Purkinje neurons.
Authors: Authors: Raman IM, Bean BP.
Ann N Y Acad Sci
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Na+ channels must deactivate to recover from inactivation.
Authors: Authors: Kuo CC, Bean BP.
Neuron
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Pharmacology of calcium channels in cardiac muscle, vascular muscle, and neurons.
Authors: Authors: Bean BP.
Am J Hypertens
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Mechanisms of calcium channel modulation by beta-adrenergic agents and dihydropyridine calcium agonists.
Authors: Authors: Tsien RW, Bean BP, Hess P, Lansman JB, Nilius B, Nowycky MC.
J Mol Cell Cardiol
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Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons.
Authors: Authors: Wainger BJ, Kiskinis E, Mellin C, Wiskow O, Han SS, Sandoe J, Perez NP, Williams LA, Lee S, Boulting G, Berry JD, Brown RH, Cudkowicz ME, Bean BP, Eggan K, Woolf CJ.
Cell Rep
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Selectively targeting pain in the trigeminal system.
Authors: Authors: Kim HY, Kim K, Li HY, Chung G, Park CK, Kim JS, Jung SJ, Lee MK, Ahn DK, Hwang SJ, Kang Y, Binshtok AM, Bean BP, Woolf CJ, Oh SB.
Pain
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