Bruce Bean, PhD
Robert Winthrop Professor of Neurobiology, Harvard Medical School
Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.
Block of N-methyl-D-aspartate-activated current by the anticonvulsant MK-801: selective binding to open channels.
Pore dilation reconsidered.
Inhibition of neuronal voltage-gated sodium channels by brilliant blue G.
Roles of subthreshold calcium current and sodium current in spontaneous firing of mouse midbrain dopamine neurons.
Inactivation and recovery of sodium currents in cerebellar Purkinje neurons: evidence for two mechanisms.
Voltage-dependent calcium channels in rat midbrain dopamine neurons: modulation by dopamine and GABAB receptors.
P-type calcium channels blocked by the spider toxin omega-Aga-IVA.
Authors: Authors: Mintz IM, Venema VJ, Swiderek KM, Lee TD, Bean BP, Adams ME.
Nature
View full abstract on Pubmed
Nature
View full abstract on Pubmed
Two ATP-activated conductances in bullfrog atrial cells.
Activation of Ih and TTX-sensitive sodium current at subthreshold voltages during CA1 pyramidal neuron firing.
Incomplete inactivation and rapid recovery of voltage-dependent sodium channels during high-frequency firing in cerebellar Purkinje neurons.