Bruce Bean, PhD
Robert Winthrop Professor of Neurobiology, Harvard Medical School
Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.
Ionic currents underlying spontaneous action potentials in isolated cerebellar Purkinje neurons.
Inhibition of P-type and N-type calcium channels by dopamine receptor antagonists.
Calcium channels. Gating for the physiologist.
Nitrendipine block of cardiac calcium channels: high-affinity binding to the inactivated state.
The Role of CaV2.1 Channel Facilitation in Synaptic Facilitation.
Authors: Authors: Weyrer C, Turecek J, Niday Z, Liu PW, Nanou E, Catterall WA, Bean BP, Regehr WG.
Cell Rep
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Cell Rep
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Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block.
Authors: Authors: Brenneis C, Kistner K, Puopolo M, Jo S, Roberson D, Sisignano M, Segal D, Cobos EJ, Wainger BJ, Labocha S, Ferreirós N, von Hehn C, Tran J, Geisslinger G, Reeh PW, Bean BP, Woolf CJ.
Br J Pharmacol
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Br J Pharmacol
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Sodium entry during action potentials of mammalian neurons: incomplete inactivation and reduced metabolic efficiency in fast-spiking neurons.
Mechanism of spontaneous firing in dorsomedial suprachiasmatic nucleus neurons.
Mibefradil inhibition of T-type calcium channels in cerebellar purkinje neurons.
Block of calcium channels in rat neurons by synthetic omega-Aga-IVA.