Bruce Bean, PhD
Robert Winthrop Professor of Neurobiology, Harvard Medical School
Bruce Bean is Robert Winthrop Professor of Neurobiology at Harvard Medical School. Bean graduated from Harvard College, received a Ph.D. in Biophysics from the University of Rochester, did postdoctoral work with Richard W. Tsien at the Yale School of Medicine, and has previously held faculty positions at the University of Iowa and the Vollum Institute of Oregon Health Sciences University. His research interests are in the electrophysiology of neurons and muscle and in using ion channels to develop new therapeutic treatments.
Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice.
Protein kinase C modulates glutamate receptor inhibition of Ca2+ channels and synaptic transmission.
Nonlinear charge movement in mammalian cardiac ventricular cells. Components from Na and Ca channel gating.
Sodium channel inactivation in the crayfish giant axon. Must channels open before inactivating?
Cell-Autonomous Excitation of Midbrain Dopamine Neurons by Endocannabinoid-Dependent Lipid Signaling.
Transient sodium current at subthreshold voltages: activation by EPSP waveforms.
Inhibition of nociceptors by TRPV1-mediated entry of impermeant sodium channel blockers.
Roles of tetrodotoxin (TTX)-sensitive Na+ current, TTX-resistant Na+ current, and Ca2+ current in the action potentials of nociceptive sensory neurons.
Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons.
Inhibition of calcium channels in rat CA3 pyramidal neurons by a metabotropic glutamate receptor.