Chenghua Gu, PhD

Professor of Neurobiology, Harvard Medical School
Peripheral nerve-derived VEGF promotes arterial differentiation via neuropilin 1-mediated positive feedback.
Authors: Authors: Mukouyama YS, Gerber HP, Ferrara N, Gu C, Anderson DJ.
Development
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Multiphasic modulation of cholinergic interneurons by nigrostriatal afferents.
Authors: Authors: Straub C, Tritsch NX, Hagan NA, Gu C, Sabatini BL.
J Neurosci
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Semaphorin 3E and plexin-D1 control vascular pattern independently of neuropilins.
Authors: Authors: Gu C, Yoshida Y, Livet J, Reimert DV, Mann F, Merte J, Henderson CE, Jessell TM, Kolodkin AL, Ginty DD.
Science
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An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling.
Authors: Authors: Tata A, Stoppel DC, Hong S, Ben-Zvi A, Xie T, Gu C.
J Cell Biol
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Vascular endothelial growth factor controls neuronal migration and cooperates with Sema3A to pattern distinct compartments of the facial nerve.
Authors: Authors: Schwarz Q, Gu C, Fujisawa H, Sabelko K, Gertsenstein M, Nagy A, Taniguchi M, Kolodkin AL, Ginty DD, Shima DT, Ruhrberg C.
Genes Dev
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Mfsd2a is critical for the formation and function of the blood-brain barrier.
Authors: Authors: Ben-Zvi A, Lacoste B, Kur E, Andreone BJ, Mayshar Y, Yan H, Gu C.
Nature
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Neuropilin-1 conveys semaphorin and VEGF signaling during neural and cardiovascular development.
Authors: Authors: Gu C, Rodriguez ER, Reimert DV, Shu T, Fritzsch B, Richards LJ, Kolodkin AL, Ginty DD.
Dev Cell
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Midbrain dopamine neurons sustain inhibitory transmission using plasma membrane uptake of GABA, not synthesis.
Authors: Authors: Tritsch NX, Oh WJ, Gu C, Sabatini BL.
Elife
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Characterization of neuropilin-1 structural features that confer binding to semaphorin 3A and vascular endothelial growth factor 165.
Authors: Authors: Gu C, Limberg BJ, Whitaker GB, Perman B, Leahy DJ, Rosenbaum JS, Ginty DD, Kolodkin AL.
J Biol Chem
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Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism.
Authors: Authors: Oh WJ, Gu C.
Neuron
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