Clifford Woolf, PhD, MB, BCh
Professor of Neurology, Boston Children's Hospital
CNS injury: IL-33 sounds the alarm.
Sensitivity and sensitisation in relation to pain severity in knee osteoarthritis: trait or state?
Authors: Authors: Neogi T, Frey-Law L, Scholz J, Niu J, Arendt-Nielsen L, Woolf C, Nevitt M, Bradley L, Felson DT.
Ann Rheum Dis
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Ann Rheum Dis
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Deconstructing the neuropathic pain phenotype to reveal neural mechanisms.
Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1.
Authors: Authors: Costigan M, Belfer I, Griffin RS, Dai F, Barrett LB, Coppola G, Wu T, Kiselycznyk C, Poddar M, Lu Y, Diatchenko L, Smith S, Cobos EJ, Zaykin D, Allchorne A, Gershon E, Livneh J, Shen PH, Nikolajsen L, Karppinen J, Männikkö M, Kelempisioti A, Goldman D, Maixner W, Geschwind DH, Max MB, Seltzer Z, Woolf CJ.
Brain
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Brain
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Capsaicin combined with local anesthetics preferentially prolongs sensory/nociceptive block in rat sciatic nerve.
Authors: Authors: Gerner P, Binshtok AM, Wang CF, Hevelone ND, Bean BP, Woolf CJ, Wang GK.
Anesthesiology
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Anesthesiology
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Central sensitization: uncovering the relation between pain and plasticity.
Role of the peripheral benzodiazepine receptor in sensory neuron regeneration.
Peripheral noxious stimulation induces phosphorylation of the NMDA receptor NR1 subunit at the PKC-dependent site, serine-896, in spinal cord dorsal horn neurons.
Authors: Authors: Brenner GJ, Ji RR, Shaffer S, Woolf CJ.
Eur J Neurosci
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Eur J Neurosci
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p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.
No DREAM, No pain. Closing the spinal gate.