Clifford Woolf, PhD, MB, BCh
Professor of Neurology, Boston Children's Hospital
p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia.
Interleukin-1beta-mediated induction of Cox-2 in the CNS contributes to inflammatory pain hypersensitivity.
Authors: Authors: Samad TA, Moore KA, Sapirstein A, Billet S, Allchorne A, Poole S, Bonventre JV, Woolf CJ.
Nature
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Nature
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Diversity of expression of the sensory neuron-specific TTX-resistant voltage-gated sodium ion channels SNS and SNS2.
Authors: Authors: Amaya F, Decosterd I, Samad TA, Plumpton C, Tate S, Mannion RJ, Costigan M, Woolf CJ.
Mol Cell Neurosci
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Mol Cell Neurosci
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Peripheral inflammation increases the capsaicin sensitivity of dorsal root ganglion neurons in a nerve growth factor-dependent manner.
Authors: Authors: Nicholas RS, Winter J, Wren P, Bergmann R, Woolf CJ.
Neuroscience
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Neuroscience
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The progressive tactile hyperalgesia induced by peripheral inflammation is nerve growth factor dependent.