Clifford Woolf, PhD, MB, BCh

Professor of Neurology, Boston Children's Hospital
Overcoming obstacles to developing new analgesics.
Authors: Authors: Woolf CJ.
Nat Med
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Nociceptors are interleukin-1beta sensors.
Authors: Authors: Binshtok AM, Wang H, Zimmermann K, Amaya F, Vardeh D, Shi L, Brenner GJ, Ji RR, Bean BP, Woolf CJ, Samad TA.
J Neurosci
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Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors.
Authors: Authors: Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R.
Nat Neurosci
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Mutant SPTLC1 dominantly inhibits serine palmitoyltransferase activity in vivo and confers an age-dependent neuropathy.
Authors: Authors: McCampbell A, Truong D, Broom DC, Allchorne A, Gable K, Cutler RG, Mattson MP, Woolf CJ, Frosch MP, Harmon JM, Dunn TM, Brown RH.
Hum Mol Genet
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Axonal injury-dependent induction of the peripheral benzodiazepine receptor in small-diameter adult rat primary sensory neurons.
Authors: Authors: Karchewski LA, Bloechlinger S, Woolf CJ.
Eur J Neurosci
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A conditional deletion of the NR1 subunit of the NMDA receptor in adult spinal cord dorsal horn reduces NMDA currents and injury-induced pain.
Authors: Authors: South SM, Kohno T, Kaspar BK, Hegarty D, Vissel B, Drake CT, Ohata M, Jenab S, Sailer AW, Malkmus S, Masuyama T, Horner P, Bogulavsky J, Gage FH, Yaksh TL, Woolf CJ, Heinemann SF, Inturrisi CE.
J Neurosci
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The pattern of expression of the voltage-gated sodium channels Na(v)1.8 and Na(v)1.9 does not change in uninjured primary sensory neurons in experimental neuropathic pain models.
Authors: Authors: Decosterd I, Ji RR, Abdi S, Tate S, Woolf CJ.
Pain
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Turbocharging neurons for growth: accelerating regeneration in the adult CNS.
Authors: Authors: Woolf CJ.
Nat Neurosci
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Nociceptive-specific activation of ERK in spinal neurons contributes to pain hypersensitivity.
Authors: Authors: Ji RR, Baba H, Brenner GJ, Woolf CJ.
Nat Neurosci
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High efficiency gene transfer to the central nervous system of rodents and primates using herpes virus vectors lacking functional ICP27 and ICP34.5.
Authors: Authors: Howard MK, Kershaw T, Gibb B, Storey N, MacLean AR, Zeng BY, Tel BC, Jenner P, Brown SM, Woolf CJ, Anderson PN, Coffin RS, Latchman DS.
Gene Ther
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