David Ginty, PhD
Edward R. and Anne G. Lefler Professor of Neurobiology, Harvard Medical School
Growth and survival signals controlling sympathetic nervous system development.
Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.
An NGF-TrkA-mediated retrograde signal to transcription factor CREB in sympathetic neurons.
Authors: Authors: Riccio A, Pierchala BA, Ciarallo CL, Ginty DD.
Science
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Science
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A pyrene fluorescence technique and microchamber for measurement of oxygen consumption of single isolated axons.
Time-Resolved Fast Mammalian Behavior Reveals the Complexity of Protective Pain Responses.
Authors: Authors: Browne LE, Latremoliere A, Lehnert BP, Grantham A, Ward C, Alexandre C, Costigan M, Michoud F, Roberson DP, Ginty DD, Woolf CJ.
Cell Rep
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Cell Rep
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Long-distance retrograde neurotrophic factor signalling in neurons.
The brain-derived neurotrophic factor receptor TrkB is critical for the acquisition but not expression of conditioned incentive value.
Authors: Authors: Johnson AW, Chen X, Crombag HS, Zhang C, Smith DR, Shokat KM, Gallagher M, Holland PC, Ginty DD.
Eur J Neurosci
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Eur J Neurosci
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Restricted inactivation of serum response factor to the cardiovascular system.
Authors: Authors: Miano JM, Ramanan N, Georger MA, de Mesy Bentley KL, Emerson RL, Balza RO, Xiao Q, Weiler H, Ginty DD, Misra RP.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Neuropilin-2 mediates axonal fasciculation, zonal segregation, but not axonal convergence, of primary accessory olfactory neurons.
Authors: Authors: Cloutier JF, Giger RJ, Koentges G, Dulac C, Kolodkin AL, Ginty DD.
Neuron
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Neuron
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Coupling of the RAS-MAPK pathway to gene activation by RSK2, a growth factor-regulated CREB kinase.