David Ginty, PhD

Edward R. and Anne G. Lefler Professor of Neurobiology, Harvard Medical School
Dynamic regulation of neuronal NO synthase transcription by calcium influx through a CREB family transcription factor-dependent mechanism.
Authors: Authors: Sasaki M, Gonzalez-Zulueta M, Huang H, Herring WJ, Ahn S, Ginty DD, Dawson VL, Dawson TM.
Proc Natl Acad Sci U S A
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Membrane depolarization and calcium influx stimulate MEK and MAP kinase via activation of Ras.
Authors: Authors: Rosen LB, Ginty DD, Weber MJ, Greenberg ME.
Neuron
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Peripheral Mechanosensory Neuron Dysfunction Underlies Tactile and Behavioral Deficits in Mouse Models of ASDs.
Authors: Authors: Orefice LL, Zimmerman AL, Chirila AM, Sleboda SJ, Head JP, Ginty DD.
Cell
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Recruitment of actin modifiers to TrkA endosomes governs retrograde NGF signaling and survival.
Authors: Authors: Harrington AW, St Hillaire C, Zweifel LS, Glebova NO, Philippidou P, Halegoua S, Ginty DD.
Cell
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Retrograde control of neural circuit formation.
Authors: Authors: Deppmann CD, Ginty DD.
Cell
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A neurotrophin signaling cascade coordinates sympathetic neuron development through differential control of TrkA trafficking and retrograde signaling.
Authors: Authors: Kuruvilla R, Zweifel LS, Glebova NO, Lonze BE, Valdez G, Ye H, Ginty DD.
Cell
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Neuropilin-2 is required in vivo for selective axon guidance responses to secreted semaphorins.
Authors: Authors: Giger RJ, Cloutier JF, Sahay A, Prinjha RK, Levengood DV, Moore SE, Pickering S, Simmons D, Rastan S, Walsh FS, Kolodkin AL, Ginty DD, Geppert M.
Neuron
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A growth factor-induced kinase phosphorylates the serum response factor at a site that regulates its DNA-binding activity.
Authors: Authors: Rivera VM, Miranti CK, Misra RP, Ginty DD, Chen RH, Blenis J, Greenberg ME.
Mol Cell Biol
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Targeting Peripheral Somatosensory Neurons to Improve Tactile-Related Phenotypes in ASD Models.
Authors: Authors: Orefice LL, Mosko JR, Morency DT, Wells MF, Tasnim A, Mozeika SM, Ye M, Chirila AM, Emanuel AJ, Rankin G, Fame RM, Lehtinen MK, Feng G, Ginty DD.
Cell
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Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking.
Authors: Authors: Bai L, Lehnert BP, Liu J, Neubarth NL, Dickendesher TL, Nwe PH, Cassidy C, Woodbury CJ, Ginty DD.
Cell
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