David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
A dominant-negative herpesvirus protein inhibits intranuclear targeting of viral proteins: effects on DNA replication and late gene expression.
“Viral persistence”
Authors: Authors: Ahmed R, Morrison LA, Knipe DM
In: Viral Pathogenesis
In: Viral Pathogenesis
"Immunization against genital herpes disease with a replication-defective mutant of HSV-2"
Authors: Authors: Knipe DM, Da Costa X, Morrison LA, Bourne N, Stanberry LR
In Vaccines 95
In Vaccines 95
Potential role for herpes simplex virus ICP8 DNA replication protein in stimulation of late gene expression.
Alternative mechanisms for activation of human immunodeficiency virus enhancer in T cells.
Mutations in the major DNA-binding protein gene of herpes simplex virus type 1 result in increased levels of viral gene expression.
Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein.
Authors: Authors: Lodish HF, Katz FN, Rothman JE, Knipe DM.
Birth Defects Orig Artic Ser
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Birth Defects Orig Artic Ser
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A digenic human immunodeficiency characterized by IFNAR1 and IFNGR2 mutations.
Authors: Authors: Hoyos-Bachiloglu R, Chou J, Sodroski CN, Beano A, Bainter W, Angelova M, Al Idrissi E, Habazi MK, Alghamdi HA, Almanjomi F, Al Shehri M, Elsidig N, Alaa Eldin M, Knipe DM, AlZahrani M, Geha RS.
J Clin Invest
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J Clin Invest
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Genome Sequencing and Analysis of Geographically Diverse Clinical Isolates of Herpes Simplex Virus 2.
Authors: Authors: Newman RM, Lamers SL, Weiner B, Ray SC, Colgrove RC, Diaz F, Jing L, Wang K, Saif S, Young S, Henn M, Laeyendecker O, Tobian AA, Cohen JI, Koelle DM, Quinn TC, Knipe DM.
J Virol
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J Virol
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Summary and recommendations from a National Institute of Allergy and Infectious Diseases (NIAID) workshop on "Next Generation Herpes Simplex Virus Vaccines".