David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Conformational changes in the herpes simplex virus ICP8 DNA-binding protein coincident with assembly in viral replication structures.
Authors: Authors: Uprichard SL, Knipe DM.
J Virol
View full abstract on Pubmed
Comparison of different forms of herpes simplex replication-defective mutant viruses as vaccines in a mouse model of HSV-2 genital infection.
Authors: Authors: Da Costa XJ, Morrison LA, Knipe DM.
Virology
View full abstract on Pubmed
The role of herpes simplex virus ICP27 in the regulation of UL24 gene expression by differential polyadenylation.
Authors: Authors: Hann LE, Cook WJ, Uprichard SL, Knipe DM, Coen DM.
J Virol
View full abstract on Pubmed
Analysis of phosphorylation sites of herpes simplex virus type 1 ICP4.
Authors: Authors: Xia K, DeLuca NA, Knipe DM.
J Virol
View full abstract on Pubmed
Altered properties of the herpes simplex virus ICP8 DNA-binding protein in cells infected with ICP27 mutant viruses.
Authors: Authors: Curtin KD, Knipe DM.
Virology
View full abstract on Pubmed
A deletion mutant of the latency-associated transcript of herpes simplex virus type 1 reactivates from the latent state with reduced frequency.
Authors: Authors: Leib DA, Bogard CL, Kosz-Vnenchak M, Hicks KA, Coen DM, Knipe DM, Schaffer PA.
J Virol
View full abstract on Pubmed
Identification of a herpes simplex virus function that represses late gene expression from parental viral genomes.
Authors: Authors: Godowski PJ, Knipe DM.
J Virol
View full abstract on Pubmed
Molecular genetics of herpes simplex virus. VII. Characterization of a temperature-sensitive mutant produced by in vitro mutagenesis and defective in DNA synthesis and accumulation of gamma polypeptides.
Authors: Authors: Conley AJ, Knipe DM, Jones PC, Roizman B.
J Virol
View full abstract on Pubmed
Translation of individual species of vesicular stomatitis viral mRNA.
Authors: Authors: Knipe D, Rose JK, Lodish HF.
J Virol
View full abstract on Pubmed
Generation of an Oncolytic Herpes Simplex Virus 1 Expressing Human MelanA.
Authors: Authors: Boscheinen JB, Thomann S, Knipe DM, DeLuca N, Schuler-Thurner B, Gross S, Dörrie J, Schaft N, Bach C, Rohrhofer A, Werner-Klein M, Schmidt B, Schuster P.
Front Immunol
View full abstract on Pubmed