David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Evidence for differences in immunologic and pathogenesis properties of herpes simplex virus 2 strains from the United States and South Africa.
Authors: Authors: Dudek TE, Torres-Lopez E, Crumpacker C, Knipe DM.
J Infect Dis
View full abstract on Pubmed
J Infect Dis
View full abstract on Pubmed
Herpesvirus tegument protein activates NF-kappaB signaling through the TRAF6 adaptor protein.
Authors: Authors: Liu X, Fitzgerald K, Kurt-Jones E, Finberg R, Knipe DM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Replication-defective viruses as vaccines and vaccine vectors.
Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis.
Authors: Authors: Kurt-Jones EA, Chan M, Zhou S, Wang J, Reed G, Bronson R, Arnold MM, Knipe DM, Finberg RW.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Neither LAT nor open reading frame P mutations increase expression of spliced or intron-containing ICP0 transcripts in mouse ganglia latently infected with herpes simplex virus.
Authors: Authors: Chen SH, Lee LY, Garber DA, Schaffer PA, Knipe DM, Coen DM.
J Virol
View full abstract on Pubmed
J Virol
View full abstract on Pubmed
Herpes simplex virus infection blocks events in the G1 phase of the cell cycle.
Mechanisms of immunization with a replication-defective mutant of herpes simplex virus 1.
Mechanism of virus-induced Ig subclass shifts.
Genetic evidence for two distinct transactivation functions of the herpes simplex virus alpha protein ICP27.
Genetic studies on murine susceptibility to herpes simplex keratitis.
Authors: Authors: Foster CS, Tsai Y, Monroe JG, Campbell R, Cestari M, Wetzig R, Knipe D, Greene MI.
Clin Immunol Immunopathol
View full abstract on Pubmed
Clin Immunol Immunopathol
View full abstract on Pubmed