David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
A mutant herpesvirus protein leads to a block in nuclear localization of other viral proteins.
Authors: Authors: Knipe DM, Smith JL.
Mol Cell Biol
View full abstract on Pubmed
Definition of a series of stages in the association of two herpesviral proteins with the cell nucleus.
Authors: Authors: Knipe DM, Spang AE.
J Virol
View full abstract on Pubmed
Membrane assembly: synthesis and intracellular processing of the vesicular stomatitis viral glycoprotein.
Authors: Authors: Katz FN, Rothman JE, Knipe DM, Lodish HF.
J Supramol Struct
View full abstract on Pubmed
Maternal immunization confers protection against neonatal herpes simplex mortality and behavioral morbidity.
Authors: Authors: Patel CD, Backes IM, Taylor SA, Jiang Y, Marchant A, Pesola JM, Coen DM, Knipe DM, Ackerman ME, Leib DA.
Sci Transl Med
View full abstract on Pubmed
A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation.
Authors: Authors: Zhao J, Zeng Y, Xu S, Chen J, Shen G, Yu C, Knipe D, Yuan W, Peng J, Xu W, Zhang C, Xia Z, Feng P.
Cell Host Microbe
View full abstract on Pubmed
cGAS-mediated stabilization of IFI16 promotes innate signaling during herpes simplex virus infection.
Authors: Authors: Orzalli MH, Broekema NM, Diner BA, Hancks DC, Elde NC, Cristea IM, Knipe DM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Snapshots: chromatin control of viral infection.
Authors: Authors: Knipe DM, Lieberman PM, Jung JU, McBride AA, Morris KV, Ott M, Margolis D, Nieto A, Nevels M, Parks RJ, Kristie TM.
Virology
View full abstract on Pubmed
Discovery of a novel TLR2 signaling inhibitor with anti-viral activity.
Authors: Authors: Zhou S, Cerny AM, Bowen G, Chan M, Knipe DM, Kurt-Jones EA, Finberg RW.
Antiviral Res
View full abstract on Pubmed
Chromatin control of herpes simplex virus lytic and latent infection.
Authors: Authors: Knipe DM, Cliffe A.
Nat Rev Microbiol
View full abstract on Pubmed
Herpesviral latency-associated transcript gene promotes assembly of heterochromatin on viral lytic-gene promoters in latent infection.
Authors: Authors: Wang QY, Zhou C, Johnson KE, Colgrove RC, Coen DM, Knipe DM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed