David Knipe, PhD
Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Optimal long-term humoral responses to replication-defective herpes simplex virus require CD21/CD35 complement receptor expression on stromal cells.
Authors: Authors: Brockman MA, Verschoor A, Zhu J, Carroll MC, Knipe DM.
J Virol
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J Virol
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Proteomics of herpes simplex virus replication compartments: association of cellular DNA replication, repair, recombination, and chromatin remodeling proteins with ICP8.
Macrophage-derived complement component C4 can restore humoral immunity in C4-deficient mice.
Authors: Authors: Gadjeva M, Verschoor A, Brockman MA, Jezak H, Shen LM, Knipe DM, Carroll MC.
J Immunol
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J Immunol
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Vaccine protection against simian immunodeficiency virus by recombinant strains of herpes simplex virus.
Authors: Authors: Murphy CG, Lucas WT, Means RE, Czajak S, Hale CL, Lifson JD, Kaur A, Johnson RP, Knipe DM, Desrosiers RC.
J Virol
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J Virol
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Th1-associated immune responses to beta-galactosidase expressed by a replication-defective herpes simplex virus.
Authors: Authors: Brubaker JO, Thompson CM, Morrison LA, Knipe DM, Siber GR, Finberg RW.
J Immunol
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J Immunol
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Preexisting nuclear architecture defines the intranuclear location of herpesvirus DNA replication structures.
Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.
Authors: Authors: Bush M, Yager DR, Gao M, Weisshart K, Marcy AI, Coen DM, Knipe DM.
J Virol
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J Virol
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Mapping of the transcriptional initiation site of the herpes simplex virus type 1 ICP8 gene in infected and transfected cells.
Thermolabile in vivo DNA-binding activity associated with a protein encoded by mutants of herpes simplex virus type 1.
Localization of two cellular forms of the vesicular stomatitis viral glycoprotein.