David Knipe, PhD

Higgins Professor of Microbiology and Molecular Genetics, Harvard Medical School
Classification of human Herpesviridae proteins using Domain-architecture Aware Inference of Orthologs (DAIO).
Authors: Authors: Zmasek CM, Knipe DM, Pellett PE, Scheuermann RH.
Virology
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A Herpesviral Lytic Protein Regulates the Structure of Latent Viral Chromatin.
Authors: Authors: Raja P, Lee JS, Pan D, Pesola JM, Coen DM, Knipe DM.
MBio
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Inhibition of LSD1 reduces herpesvirus infection, shedding, and recurrence by promoting epigenetic suppression of viral genomes.
Authors: Authors: Hill JM, Quenelle DC, Cardin RD, Vogel JL, Clement C, Bravo FJ, Foster TP, Bosch-Marce M, Raja P, Lee JS, Bernstein DI, Krause PR, Knipe DM, Kristie TM.
Sci Transl Med
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Decreasing herpes simplex viral infectivity in solution by surface-immobilized and suspended N,N-dodecyl,methyl-polyethylenimine.
Authors: Authors: Larson AM, Oh HS, Knipe DM, Klibanov AM.
Pharm Res
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Herpes simplex virus VP16, but not ICP0, is required to reduce histone occupancy and enhance histone acetylation on viral genomes in U2OS osteosarcoma cells.
Authors: Authors: Hancock MH, Cliffe AR, Knipe DM, Smiley JR.
J Virol
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Immunization with a replication-defective herpes simplex virus 2 mutant reduces herpes simplex virus 1 infection and prevents ocular disease.
Authors: Authors: van Lint AL, Torres-Lopez E, Knipe DM.
Virology
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The role of toll-like receptors in herpes simplex infection in neonates.
Authors: Authors: Kurt-Jones EA, Belko J, Yu C, Newburger PE, Wang J, Chan M, Knipe DM, Finberg RW.
J Infect Dis
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C-terminal region of herpes simplex virus ICP8 protein needed for intranuclear localization.
Authors: Authors: Taylor TJ, Knipe DM.
Virology
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Herpes simplex virus 1 ICP27 is required for transcription of two viral late (gamma 2) genes in infected cells.
Authors: Authors: Jean S, LeVan KM, Song B, Levine M, Knipe DM.
Virology
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Accumulation of viral transcripts and DNA during establishment of latency by herpes simplex virus.
Authors: Authors: Kramer MF, Chen SH, Knipe DM, Coen DM.
J Virol
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