Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Human cytomegalovirus mutant with sequence-dependent resistance to the phosphorothioate oligonucleotide fomivirsen (ISIS 2922).
Authors: Authors: Mulamba GB, Hu A, Azad RF, Anderson KP, Coen DM.
Antimicrob Agents Chemother
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Induction of transcription by a viral regulatory protein depends on the relative strengths of functional TATA boxes.
Authors: Authors: Cook WJ, Gu B, DeLuca NA, Moynihan EB, Coen DM.
Mol Cell Biol
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Unusual regulation of expression of the herpes simplex virus DNA polymerase gene.
Authors: Authors: Wobbe KK, Digard P, Staknis D, Coen DM.
J Virol
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Correct intranuclear localization of herpes simplex virus DNA polymerase requires the viral ICP8 DNA-binding protein.
Authors: Authors: Bush M, Yager DR, Gao M, Weisshart K, Marcy AI, Coen DM, Knipe DM.
J Virol
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Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.
Authors: Authors: Coen DM, Goldstein DJ, Weller SK.
Antimicrob Agents Chemother
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Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors.
Authors: Authors: Chiou HC, Weller SK, Coen DM.
Virology
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Membrane proteins synthesized but not processed by isolated maize chloroplasts.
Authors: Authors: Grebanier AE, Coen DM, Rich A, Bogorad L.
J Cell Biol
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HSV-1 DNA polymerase 3'-5' exonuclease-deficient mutant D368A exhibits severely reduced viral DNA synthesis and polymerase expression.
Authors: Authors: Lawler JL, Coen DM.
J Gen Virol
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Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Authors: Authors: Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H.
Proc Natl Acad Sci U S A
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A mutation deleting sequences encoding the amino terminus of human cytomegalovirus UL84 impairs interaction with UL44 and capsid localization.
Authors: Authors: Strang BL, Bender BJ, Sharma M, Pesola JM, Sanders RL, Spector DH, Coen DM.
J Virol
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