Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
The cytomegalovirus DNA polymerase subunit UL44 forms a C clamp-shaped dimer.
Authors: Authors: Appleton BA, Loregian A, Filman DJ, Coen DM, Hogle JM.
Mol Cell
View full abstract on Pubmed
Identification, localization, and regulation of expression of the UL24 protein of herpes simplex virus type 1.
Authors: Authors: Pearson A, Coen DM.
J Virol
View full abstract on Pubmed
Acyclovir is phosphorylated by the human cytomegalovirus UL97 protein.
Authors: Authors: Talarico CL, Burnette TC, Miller WH, Smith SL, Davis MG, Stanat SC, Ng TI, He Z, Coen DM, Roizman B, Biron KK.
Antimicrob Agents Chemother
View full abstract on Pubmed
A viral function represses accumulation of transcripts from productive-cycle genes in mouse ganglia latently infected with herpes simplex virus.
Authors: Authors: Chen SH, Kramer MF, Schaffer PA, Coen DM.
J Virol
View full abstract on Pubmed
Acyclovir-resistant, pathogenic herpesviruses.
Authors: Authors: Coen DM.
Trends Microbiol
View full abstract on Pubmed
Expanded spectrum of viral therapy in the treatment of nervous system tumors.
Authors: Authors: Markert JM, Coen DM, Malick A, Mineta T, Martuza RL.
J Neurosurg
View full abstract on Pubmed
A novel functional domain of an alpha-like DNA polymerase. The binding site on the herpes simplex virus polymerase for the viral UL42 protein.
Authors: Authors: Digard P, Coen DM.
J Biol Chem
View full abstract on Pubmed
Low levels of herpes simplex virus thymidine- thymidylate kinase are not limiting for sensitivity to certain antiviral drugs or for latency in a mouse model.
Authors: Authors: Coen DM, Irmiere AF, Jacobson JG, Kerns KM.
Virology
View full abstract on Pubmed
Generation of genetic diversity in herpes simplex virus: an antimutator phenotype maps to the DNA polymerase locus.
Authors: Authors: Hall JD, Coen DM, Fisher BL, Weisslitz M, Randall S, Almy RE, Gelep PT, Schaffer PA.
Virology
View full abstract on Pubmed
Mitochondrial genetics. VI. The petite mutation in Saccharomyces cerevisiae: interrelations between the loss of the p+ factor and the loss of the drug resistance mitochondrial genetic markers.
Authors: Authors: Deutsch J, Dujon B, Netter P, Petrochilo E, Slonimski PP, Bolotin-Fukuhara M, Coen D.
Genetics
View full abstract on Pubmed