Donald Coen, PhD
Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Evidence for a novel regulatory pathway for herpes simplex virus gene expression in trigeminal ganglion neurons.
Authors: Authors: Kosz-Vnenchak M, Jacobson J, Coen DM, Knipe DM.
J Virol
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J Virol
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The implications of resistance to antiviral agents for herpesvirus drug targets and drug therapy.
Herpes simplex virus ribonucleotide reductase mutants are hypersensitive to acyclovir.
Authors: Authors: Coen DM, Goldstein DJ, Weller SK.
Antimicrob Agents Chemother
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Antimicrob Agents Chemother
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Mutations in the herpes simplex virus major DNA-binding protein gene leading to altered sensitivity to DNA polymerase inhibitors.
Membrane proteins synthesized but not processed by isolated maize chloroplasts.
Authors: Authors: Grebanier AE, Coen DM, Rich A, Bogorad L.
J Cell Biol
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J Cell Biol
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Herpes Simplex Virus 1 Lytic Infection Blocks MicroRNA (miRNA) Biogenesis at the Stage of Nuclear Export of Pre-miRNAs.
Authors: Authors: Pan D, Li G, Morris-Love J, Qi S, Feng L, Mertens ME, Jurak I, Knipe DM, Coen DM.
MBio
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MBio
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Preparation of the Human Cytomegalovirus Nuclear Egress Complex and Associated Proteins.
The pre-NH(2)-terminal domain of the herpes simplex virus 1 DNA polymerase catalytic subunit is required for efficient viral replication.
Interaction of the human cytomegalovirus uracil DNA glycosylase UL114 with the viral DNA polymerase catalytic subunit UL54.
Inhibition of translation by a short element in the 5' leader of the herpes simplex virus 1 DNA polymerase transcript.