Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
The crystal structure of an unusual processivity factor, herpes simplex virus UL42, bound to the C terminus of its cognate polymerase.
Authors: Authors: Zuccola HJ, Filman DJ, Coen DM, Hogle JM.
Mol Cell
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Penciclovir and pathogenesis phenotypes of drug-resistant Herpes simplex virus mutants.
Authors: Authors: Pelosi E, Mulamba GB, Coen DM.
Antiviral Res
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Synergistic effects on ganglionic herpes simplex virus infections by mutations or drugs that inhibit the viral polymerase and thymidine kinase.
Authors: Authors: Jacobson J, Kramer M, Rozenberg F, Hu A, Coen DM.
Virology
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A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives.
Authors: Authors: Sullivan V, Biron KK, Talarico C, Stanat SC, Davis M, Pozzi LM, Coen DM.
Antimicrob Agents Chemother
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P element regulatory products enhance zeste repression of a P[white duplicated] transgene in Drosophila melanogaster.
Authors: Authors: Coen D.
Genetics
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Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.
Authors: Authors: Leib DA, Coen DM, Bogard CL, Hicks KA, Yager DR, Knipe DM, Tyler KL, Schaffer PA.
J Virol
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Herpes simplex virus mutants resistant to arabinosyladenine in the presence of deoxycoformycin.
Authors: Authors: Fleming HE, Coen DM.
Antimicrob Agents Chemother
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