Donald Coen, PhD

Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Translational recoding induced by G-rich mRNA sequences that form unusual structures.
Authors: Authors: Horsburgh BC, Kollmus H, Hauser H, Coen DM.
Cell
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A net +1 frameshift permits synthesis of thymidine kinase from a drug-resistant herpes simplex virus mutant.
Authors: Authors: Hwang CB, Horsburgh B, Pelosi E, Roberts S, Digard P, Coen DM.
Proc Natl Acad Sci U S A
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A protein kinase homologue controls phosphorylation of ganciclovir in human cytomegalovirus-infected cells.
Authors: Authors: Sullivan V, Talarico CL, Stanat SC, Davis M, Coen DM, Biron KK.
Nature
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Specific inhibitors of herpes simplex virus thymidine kinase diminish reactivation of latent virus from explanted murine ganglia.
Authors: Authors: Leib DA, Ruffner KL, Hildebrand C, Schaffer PA, Wright GE, Coen DM.
Antimicrob Agents Chemother
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Analysis of the transcript of the herpes simplex virus DNA polymerase gene provides evidence that polymerase expression is inefficient at the level of translation.
Authors: Authors: Yager DR, Coen DM.
J Virol
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Genetic analysis of temperature-sensitive mutants of HSV-1: the combined use of complementation and physical mapping for cistron assignment.
Authors: Authors: Weller SK, Aschman DP, Sacks WR, Coen DM, Schaffer PA.
Virology
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Mitochondrial nucleic acids in the petite colonie mutants: deletions and repetition of genes.
Authors: Authors: Faye G, Fukuhara H, Grandchamp C, Lazowska J, Michel F, Casey J, Getz GS, Locker J, Rabinowitz M, Bolotin-Fukuhara M, Coen D, Deutsch J, Dujon B, Netter P, Slonimski PP.
Biochimie
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