Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Reversal of type 1 diabetes in mice.
Endothelial signaling during development.
Early mouse endoderm is patterned by soluble factors from adjacent germ layers.
Induction of axial mesoderm by zDVR-1, the zebrafish orthologue of Xenopus Vg1.
A truncated activin receptor inhibits mesoderm induction and formation of axial structures in Xenopus embryos.
Interaction between peptide growth factors and homoeobox genes in the establishment of antero-posterior polarity in frog embryos.
Circadian Entrainment Triggers Maturation of Human In Vitro Islets.
Authors: Authors: Alvarez-Dominguez JR, Donaghey J, Rasouli N, Kenty JHR, Helman A, Charlton J, Straubhaar JR, Meissner A, Melton DA.
Cell Stem Cell
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Cell Stem Cell
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Corrigendum: Generation of stem cell-derived ß-cells from patients with type 1 diabetes.
Authors: Authors: Millman JR, Xie C, Van Dervort A, Gürtler M, Pagliuca FW, Melton DA.
Nat Commun
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Nat Commun
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Betatrophin: a hormone that controls pancreatic ß cell proliferation.
A small molecule that directs differentiation of human ESCs into the pancreatic lineage.
Authors: Authors: Chen S, Borowiak M, Fox JL, Maehr R, Osafune K, Davidow L, Lam K, Peng LF, Schreiber SL, Rubin LL, Melton D.
Nat Chem Biol
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Nat Chem Biol
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