Douglas Melton, PhD
Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development.
Authors: Authors: Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA.
Cell Rep
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Cell Rep
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Applied Developmental Biology: Making Human Pancreatic Beta Cells for Diabetics.
Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme.
Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2.
Authors: Authors: Huangfu D, Osafune K, Maehr R, Guo W, Eijkelenboom A, Chen S, Muhlestein W, Melton DA.
Nat Biotechnol
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Nat Biotechnol
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Nuclear reprogramming of somatic cells after fusion with human embryonic stem cells.
Direct lineage tracing reveals the ontogeny of pancreatic cell fates during mouse embryogenesis.
Mixer, a homeobox gene required for endoderm development.
Vertebrate embryonic induction: mesodermal and neural patterning.
Injected Wnt RNA induces a complete body axis in Xenopus embryos.
Involvement of the Xenopus homeobox gene Xhox3 in pattern formation along the anterior-posterior axis.