Douglas Melton, PhD

Xander University Professor of Stem Cell and Regenerative Biology, Faculty of Arts & Sciences
Charting cellular identity during human in vitro ß-cell differentiation.
Authors: Authors: Veres A, Faust AL, Bushnell HL, Engquist EN, Kenty JH, Harb G, Poh YC, Sintov E, Gürtler M, Pagliuca FW, Peterson QP, Melton DA.
Nature
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Angptl4 links a-cell proliferation following glucagon receptor inhibition with adipose tissue triglyceride metabolism.
Authors: Authors: Ben-Zvi D, Barrandon O, Hadley S, Blum B, Peterson QP, Melton DA.
Proc Natl Acad Sci U S A
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Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3.
Authors: Authors: Blum B, Hrvatin S, Schuetz C, Bonal C, Rezania A, Melton DA.
Nat Biotechnol
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Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds.
Authors: Authors: Huangfu D, Maehr R, Guo W, Eijkelenboom A, Snitow M, Chen AE, Melton DA.
Nat Biotechnol
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Direct regulation of intestinal fate by Notch.
Authors: Authors: Stanger BZ, Datar R, Murtaugh LC, Melton DA.
Proc Natl Acad Sci U S A
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"Stemness": transcriptional profiling of embryonic and adult stem cells.
Authors: Authors: Ramalho-Santos M, Yoon S, Matsuzaki Y, Mulligan RC, Melton DA.
Science
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Mutant Vg1 ligands disrupt endoderm and mesoderm formation in Xenopus embryos.
Authors: Authors: Joseph EM, Melton DA.
Development
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Studies with a Xenopus BMP receptor suggest that ventral mesoderm-inducing signals override dorsal signals in vivo.
Authors: Authors: Graff JM, Thies RS, Song JJ, Celeste AJ, Melton DA.
Cell
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Pre-existent pattern in Xenopus animal pole cells revealed by induction with activin.
Authors: Authors: Sokol S, Melton DA.
Nature
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The process of localizing a maternal messenger RNA in Xenopus oocytes.
Authors: Authors: Yisraeli JK, Sokol S, Melton DA.
Development
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