George Church, PhD

Robert Winthrop Professor of Genetics, Harvard Medical School
The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes.
Authors: Authors: Mao Q, Ciotlos S, Zhang RY, Ball MP, Chin R, Carnevali P, Barua N, Nguyen S, Agarwal MR, Clegg T, Connelly A, Vandewege W, Zaranek AW, Estep PW, Church GM, Drmanac R, Peters BA.
Gigascience
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Biosensor-based engineering of biosynthetic pathways.
Authors: Authors: Rogers JK, Taylor ND, Church GM.
Curr Opin Biotechnol
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Cas9 gRNA engineering for genome editing, activation and repression.
Authors: Authors: Kiani S, Chavez A, Tuttle M, Hall RN, Chari R, Ter-Ovanesyan D, Qian J, Pruitt BW, Beal J, Vora S, Buchthal J, Kowal EJ, Ebrahimkhani MR, Collins JJ, Weiss R, Church G.
Nat Methods
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Biocontainment of genetically modified organisms by synthetic protein design.
Authors: Authors: Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM.
Nature
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CRISPR/Cas9-Directed Genome Editing of Cultured Cells.
Authors: Authors: Yang L, Yang JL, Byrne S, Pan J, Church GM.
Curr Protoc Mol Biol
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Rational optimization of tolC as a powerful dual selectable marker for genome engineering.
Authors: Authors: Gregg CJ, Lajoie MJ, Napolitano MG, Mosberg JA, Goodman DB, Aach J, Isaacs FJ, Church GM.
Nucleic Acids Res
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Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.
Authors: Authors: Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM.
Nat Methods
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Next-generation carrier screening.
Authors: Authors: Umbarger MA, Kennedy CJ, Saunders P, Breton B, Chennagiri N, Emhoff J, Greger V, Hallam S, Maganzini D, Micale C, Nizzari MM, Towne CF, Church GM, Porreca GJ.
Genet Med
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Improving lambda red genome engineering in Escherichia coli via rational removal of endogenous nucleases.
Authors: Authors: Mosberg JA, Gregg CJ, Lajoie MJ, Wang HH, Church GM.
PLoS One
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Elevated coding mutation rate during the reprogramming of human somatic cells into induced pluripotent stem cells.
Authors: Authors: Ji J, Ng SH, Sharma V, Neculai D, Hussein S, Sam M, Trinh Q, Church GM, McPherson JD, Nagy A, Batada NN.
Stem Cells
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