George Church, PhD
Robert Winthrop Professor of Genetics, Harvard Medical School
A robust approach to identifying tissue-specific gene expression regulatory variants using personalized human induced pluripotent stem cells.
Authors: Authors: Lee JH, Park IH, Gao Y, Li JB, Li Z, Daley GQ, Zhang K, Church GM.
PLoS Genet
View full abstract on Pubmed
PLoS Genet
View full abstract on Pubmed
Targeted and genome-scale strategies reveal gene-body methylation signatures in human cells.
Authors: Authors: Ball MP, Li JB, Gao Y, Lee JH, LeProust EM, Park IH, Xie B, Daley GQ, Church GM.
Nat Biotechnol
View full abstract on Pubmed
Nat Biotechnol
View full abstract on Pubmed
Genome-wide expression dynamics of a marine virus and host reveal features of co-evolution.
Authors: Authors: Lindell D, Jaffe JD, Coleman ML, Futschik ME, Axmann IM, Rector T, Kettler G, Sullivan MB, Steen R, Hess WR, Church GM, Chisholm SW.
Nature
View full abstract on Pubmed
Nature
View full abstract on Pubmed
Mammalian ultraconserved elements are strongly depleted among segmental duplications and copy number variants.
Improving molecular cancer class discovery through sparse non-negative matrix factorization.
Modular epistasis in yeast metabolism.
Fluorescent in situ sequencing on polymerase colonies.
Authors: Authors: Mitra RD, Shendure J, Olejnik J, Church GM.
Anal Biochem
View full abstract on Pubmed
Anal Biochem
View full abstract on Pubmed
Analysis of optimality in natural and perturbed metabolic networks.
Authors: Authors: Segrè D, Vitkup D, Church GM.
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Proc Natl Acad Sci U S A
View full abstract on Pubmed
Dynamic simulation of the human red blood cell metabolic network.
Authors: Authors: Jamshidi N, Edwards JS, Fahland T, Church GM, Palsson BO.
Bioinformatics
View full abstract on Pubmed
Bioinformatics
View full abstract on Pubmed
Biclustering of expression data.
Authors: Authors: Cheng Y, Church GM.
Proc Int Conf Intell Syst Mol Biol
View full abstract on Pubmed
Proc Int Conf Intell Syst Mol Biol
View full abstract on Pubmed