George Church, PhD
Robert Winthrop Professor of Genetics, Harvard Medical School
Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.
Authors: Authors: Rock JM, Hopkins FF, Chavez A, Diallo M, Chase MR, Gerrick ER, Pritchard JR, Church GM, Rubin EJ, Sassetti CM, Schnappinger D, Fortune SM.
Nat Microbiol
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Nat Microbiol
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Next stop for the CRISPR revolution: RNA-guided epigenetic regulators.
Tools for the Microbiome: Nano and Beyond.
Authors: Authors: Biteen JS, Blainey PC, Cardon ZG, Chun M, Church GM, Dorrestein PC, Fraser SE, Gilbert JA, Jansson JK, Knight R, Miller JF, Ozcan A, Prather KA, Quake SR, Ruby EG, Silver PA, Taha S, van den Engh G, Weiss PS, Wong GC, Wright AT, Young TD.
ACS Nano
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ACS Nano
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Unraveling CRISPR-Cas9 genome engineering parameters via a library-on-library approach.
Authors: Authors: Chari R, Mali P, Moosburner M, Church GM.
Nat Methods
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Nat Methods
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Targeted and genome-wide sequencing reveal single nucleotide variations impacting specificity of Cas9 in human stem cells.
Authors: Authors: Yang L, Grishin D, Wang G, Aach J, Zhang CZ, Chari R, Homsy J, Cai X, Zhao Y, Fan JB, Seidman C, Seidman J, Pu W, Church G.
Nat Commun
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Nat Commun
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Fungal lysis by a soil bacterium fermenting cellulose.
Authors: Authors: Tolonen AC, Cerisy T, El-Sayyed H, Boutard M, Salanoubat M, Church GM.
Environ Microbiol
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Environ Microbiol
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The role of replicates for error mitigation in next-generation sequencing.
Optical control of mammalian endogenous transcription and epigenetic states.
Authors: Authors: Konermann S, Brigham MD, Trevino A, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F.
Nature
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Nature
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Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems.
Authors: Authors: DiCarlo JE, Norville JE, Mali P, Rios X, Aach J, Church GM.
Nucleic Acids Res
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Nucleic Acids Res
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A public resource facilitating clinical use of genomes.
Authors: Authors: Ball MP, Thakuria JV, Zaranek AW, Clegg T, Rosenbaum AM, Wu X, Angrist M, Bhak J, Bobe J, Callow MJ, Cano C, Chou MF, Chung WK, Douglas SM, Estep PW, Gore A, Hulick P, Labarga A, Lee JH, Lunshof JE, Kim BC, Kim JI, Li Z, Murray MF, Nilsen GB, Peters BA, Raman AM, Rienhoff HY, Robasky K, Wheeler MT, Vandewege W, Vorhaus DB, Yang JL, Yang L, Aach J, Ashley EA, Drmanac R, Kim SJ, Li JB, Peshkin L, Seidman CE, Seo JS, Zhang K, Rehm HL, Church GM.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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