George Church, PhD

Robert Winthrop Professor of Genetics, Harvard Medical School
Modeling the mitochondrial cardiomyopathy of Barth syndrome with induced pluripotent stem cell and heart-on-chip technologies.
Authors: Authors: Wang G, McCain ML, Yang L, He A, Pasqualini FS, Agarwal A, Yuan H, Jiang D, Zhang D, Zangi L, Geva J, Roberts AE, Ma Q, Ding J, Chen J, Wang DZ, Li K, Wang J, Wanders RJ, Kulik W, Vaz FM, Laflamme MA, Murry CE, Chien KR, Kelley RI, Church GM, Parker KK, Pu WT.
Nat Med
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The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies.
Authors: Authors: Sok D, Laserson U, Laserson J, Liu Y, Vigneault F, Julien JP, Briney B, Ramos A, Saye KF, Le K, Mahan A, Wang S, Kardar M, Yaari G, Walker LM, Simen BB, St John EP, Chan-Hui PY, Swiderek K, Kleinstein SH, Kleinstein SH, Alter G, Seaman MS, Chakraborty AK, Koller D, Wilson IA, Church GM, Burton DR, Poignard P.
PLoS Pathog
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Composability of regulatory sequences controlling transcription and translation in Escherichia coli.
Authors: Authors: Kosuri S, Goodman DB, Cambray G, Mutalik VK, Gao Y, Arkin AP, Endy D, Church GM.
Proc Natl Acad Sci U S A
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Redirector: designing cell factories by reconstructing the metabolic objective.
Authors: Authors: Rockwell G, Guido NJ, Church GM.
PLoS Comput Biol
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Accurate whole-genome sequencing and haplotyping from 10 to 20 human cells.
Authors: Authors: Peters BA, Kermani BG, Sparks AB, Alferov O, Hong P, Alexeev A, Jiang Y, Dahl F, Tang YT, Haas J, Robasky K, Zaranek AW, Lee JH, Ball MP, Peterson JE, Perazich H, Yeung G, Liu J, Chen L, Kennemer MI, Pothuraju K, Konvicka K, Tsoupko-Sitnikov M, Pant KP, Ebert JC, Nilsen GB, Baccash J, Halpern AL, Church GM, Drmanac R.
Nature
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The three-dimensional architecture of a bacterial genome and its alteration by genetic perturbation.
Authors: Authors: Umbarger MA, Toro E, Wright MA, Porreca GJ, Baù D, Hong SH, Fero MJ, Zhu LJ, Marti-Renom MA, McAdams HH, Shapiro L, Dekker J, Church GM.
Mol Cell
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Scalable gene synthesis by selective amplification of DNA pools from high-fidelity microchips.
Authors: Authors: Kosuri S, Eroshenko N, Leproust EM, Super M, Way J, Li JB, Church GM.
Nat Biotechnol
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Human genome sequencing using unchained base reads on self-assembling DNA nanoarrays.
Authors: Authors: Drmanac R, Sparks AB, Callow MJ, Halpern AL, Burns NL, Kermani BG, Carnevali P, Nazarenko I, Nilsen GB, Yeung G, Dahl F, Fernandez A, Staker B, Pant KP, Baccash J, Borcherding AP, Brownley A, Cedeno R, Chen L, Chernikoff D, Cheung A, Chirita R, Curson B, Ebert JC, Hacker CR, Hartlage R, Hauser B, Huang S, Jiang Y, Karpinchyk V, Koenig M, Kong C, Landers T, Le C, Liu J, McBride CE, Morenzoni M, Morey RE, Mutch K, Perazich H, Perry K, Peters BA, Peterson J, Pethiyagoda CL, Pothuraju K, Richter C, Rosenbaum AM, Roy S, Shafto J, Sharanhovich U, Shannon KW, Sheppy CG, Sun M, Thakuria JV, Tran A, Vu D, Zaranek AW, Wu X, Drmanac S, Oliphant AR, Banyai WC, Martin B, Ballinger DG, Church GM, Reid CA.
Science
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Meta-analysis of age-related gene expression profiles identifies common signatures of aging.
Authors: Authors: de Magalhães JP, Curado J, Church GM.
Bioinformatics
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Quantitative monitoring by polymerase colony assay of known mutations resistant to ABL kinase inhibitors.
Authors: Authors: Nardi V, Raz T, Cao X, Wu CJ, Stone RM, Cortes J, Deininger MW, Church G, Zhu J, Daley GQ.
Oncogene
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