George Church, PhD

Robert Winthrop Professor of Genetics, Harvard Medical School
Computational identification of transcription factor binding sites via a transcription-factor-centric clustering (TFCC) algorithm.
Authors: Authors: Zhu Z, Pilpel Y, Church GM.
J Mol Biol
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The Isw2 chromatin remodeling complex represses early meiotic genes upon recruitment by Ume6p.
Authors: Authors: Goldmark JP, Fazzio TG, Estep PW, Church GM, Tsukiyama T.
Cell
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Finding DNA regulatory motifs within unaligned noncoding sequences clustered by whole-genome mRNA quantitation.
Authors: Authors: Roth FP, Hughes JD, Estep PW, Church GM.
Nat Biotechnol
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Complementary recognition in condensed DNA: accelerated DNA renaturation.
Authors: Authors: Sikorav JL, Church GM.
J Mol Biol
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Optimizing complex phenotypes through model-guided multiplex genome engineering.
Authors: Authors: Kuznetsov G, Goodman DB, Filsinger GT, Landon M, Rohland N, Aach J, Lajoie MJ, Church GM.
Genome Biol
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Engineering and optimising deaminase fusions for genome editing.
Authors: Authors: Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G.
Nat Commun
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Real-time single-molecule electronic DNA sequencing by synthesis using polymer-tagged nucleotides on a nanopore array.
Authors: Authors: Fuller CW, Kumar S, Porel M, Chien M, Bibillo A, Stranges PB, Dorwart M, Tao C, Li Z, Guo W, Shi S, Korenblum D, Trans A, Aguirre A, Liu E, Harada ET, Pollard J, Bhat A, Cech C, Yang A, Arnold C, Palla M, Hovis J, Chen R, Morozova I, Kalachikov S, Russo JJ, Kasianowicz JJ, Davis R, Roever S, Church GM, Ju J.
Proc Natl Acad Sci U S A
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Genome-wide inactivation of porcine endogenous retroviruses (PERVs).
Authors: Authors: Yang L, Güell M, Niu D, George H, Lesha E, Grishin D, Aach J, Shrock E, Xu W, Poci J, Cortazio R, Wilkinson RA, Fishman JA, Church G.
Science
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Fluorescent in situ sequencing (FISSEQ) of RNA for gene expression profiling in intact cells and tissues.
Authors: Authors: Lee JH, Daugharthy ER, Scheiman J, Kalhor R, Ferrante TC, Terry R, Turczyk BM, Yang JL, Lee HS, Aach J, Zhang K, Church GM.
Nat Protoc
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Biotechnology. Regulating gene drives.
Authors: Authors: Oye KA, Esvelt K, Appleton E, Catteruccia F, Church G, Kuiken T, Lightfoot SB, McNamara J, Smidler A, Collins JP.
Science
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