George Church, PhD

Robert Winthrop Professor of Genetics, Harvard Medical School
Safeguarding CRISPR-Cas9 gene drives in yeast.
Authors: Authors: DiCarlo JE, Chavez A, Dietz SL, Esvelt KM, Church GM.
Nat Biotechnol
View full abstract on Pubmed
Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics.
Authors: Authors: Yaung SJ, Deng L, Li N, Braff JL, Church GM, Bry L, Wang HH, Gerber GK.
Mol Syst Biol
View full abstract on Pubmed
Improved cell-free RNA and protein synthesis system.
Authors: Authors: Li J, Gu L, Aach J, Church GM.
PLoS One
View full abstract on Pubmed
Realizing the potential of synthetic biology.
Authors: Authors: Church GM, Elowitz MB, Smolke CD, Voigt CA, Weiss R.
Nat Rev Mol Cell Biol
View full abstract on Pubmed
Genomically recoded organisms expand biological functions.
Authors: Authors: Lajoie MJ, Rovner AJ, Goodman DB, Aerni HR, Haimovich AD, Kuznetsov G, Mercer JA, Wang HH, Carr PA, Mosberg JA, Rohland N, Schultz PG, Jacobson JM, Rinehart J, Church GM, Isaacs FJ.
Science
View full abstract on Pubmed
Molecular threading: mechanical extraction, stretching and placement of DNA molecules from a liquid-air interface.
Authors: Authors: Payne AC, Andregg M, Kemmish K, Hamalainen M, Bowell C, Bleloch A, Klejwa N, Lehrach W, Schatz K, Stark H, Marblestone A, Church G, Own CS, Andregg W.
PLoS One
View full abstract on Pubmed
Mutants of Cre recombinase with improved accuracy.
Authors: Authors: Eroshenko N, Church GM.
Nat Commun
View full abstract on Pubmed
Enhanced multiplex genome engineering through co-operative oligonucleotide co-selection.
Authors: Authors: Carr PA, Wang HH, Sterling B, Isaacs FJ, Lajoie MJ, Xu G, Church GM, Jacobson JM.
Nucleic Acids Res
View full abstract on Pubmed
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence.
Authors: Authors: Dewey FE, Chen R, Cordero SP, Ormond KE, Caleshu C, Karczewski KJ, Whirl-Carrillo M, Wheeler MT, Dudley JT, Byrnes JK, Cornejo OE, Knowles JW, Woon M, Sangkuhl K, Gong L, Thorn CF, Hebert JM, Capriotti E, David SP, Pavlovic A, West A, Thakuria JV, Ball MP, Zaranek AW, Rehm HL, Church GM, West JS, Bustamante CD, Snyder M, Altman RB, Klein TE, Butte AJ, Ashley EA.
PLoS Genet
View full abstract on Pubmed
Reprogramming of T cells from human peripheral blood.
Authors: Authors: Loh YH, Hartung O, Li H, Guo C, Sahalie JM, Manos PD, Urbach A, Heffner GC, Grskovic M, Vigneault F, Lensch MW, Park IH, Agarwal S, Church GM, Collins JJ, Irion S, Daley GQ.
Cell Stem Cell
View full abstract on Pubmed