George Church, PhD
Robert Winthrop Professor of Genetics, Harvard Medical School
An unbiased index to quantify participant's phenotypic contribution to an open-access cohort.
Authors: Authors: Chan Y, Tung M, Garruss AS, Zaranek SW, Chan YK, Lunshof JE, Zaranek AW, Ball MP, Chou MF, Lim ET, Church GM.
Sci Rep
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Sci Rep
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A multifunctional AAV-CRISPR-Cas9 and its host response.
Authors: Authors: Chew WL, Tabebordbar M, Cheng JK, Mali P, Wu EY, Ng AH, Zhu K, Wagers AJ, Church GM.
Nat Methods
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Nat Methods
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Genetically encoded sensors enable real-time observation of metabolite production.
HEART DISEASE. Titin mutations in iPS cells define sarcomere insufficiency as a cause of dilated cardiomyopathy.
Authors: Authors: Hinson JT, Chopra A, Nafissi N, Polacheck WJ, Benson CC, Swist S, Gorham J, Yang L, Schafer S, Sheng CC, Haghighi A, Homsy J, Hubner N, Church G, Cook SA, Linke WA, Chen CS, Seidman JG, Seidman CE.
Science
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Science
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Complete Genome Sequences of T4-Like Bacteriophages RB3, RB5, RB6, RB7, RB9, RB10, RB27, RB33, RB55, RB59, and RB68.
Direct mutagenesis of thousands of genomic targets using microarray-derived oligonucleotides.
Authors: Authors: Bonde MT, Kosuri S, Genee HJ, Sarup-Lytzen K, Church GM, Sommer MO, Wang HH.
ACS Synth Biol
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ACS Synth Biol
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CRISPR-Cas-mediated targeted genome editing in human cells.
Authors: Authors: Yang L, Mali P, Kim-Kiselak C, Church G.
Methods Mol Biol
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Methods Mol Biol
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Natural reassignment of CUU and CUA sense codons to alanine in Ashbya mitochondria.
Authors: Authors: Ling J, Daoud R, Lajoie MJ, Church GM, Söll D, Lang BF.
Nucleic Acids Res
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Nucleic Acids Res
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Protein interaction discovery using parallel analysis of translated ORFs (PLATO).
Authors: Authors: Zhu J, Larman HB, Gao G, Somwar R, Zhang Z, Laserson U, Ciccia A, Pavlova N, Church G, Zhang W, Kesari S, Elledge SJ.
Nat Biotechnol
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Nat Biotechnol
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Measuring cation dependent DNA polymerase fidelity landscapes by deep sequencing.
Authors: Authors: Zamft BM, Marblestone AH, Kording K, Schmidt D, Martin-Alarcon D, Tyo K, Boyden ES, Church G.
PLoS One
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PLoS One
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