George Church, PhD

Robert Winthrop Professor of Genetics, Harvard Medical School
Methods for generating precise deletions and insertions in the genome of wild-type Escherichia coli: application to open reading frame characterization.
Authors: Authors: Link AJ, Phillips D, Church GM.
J Bacteriol
View full abstract on Pubmed
Cell-type-specific contacts to immunoglobulin enhancers in nuclei.
Authors: Authors: Church GM, Ephrussi A, Gilbert W, Tonegawa S.
Nature
View full abstract on Pubmed
Mature induced-pluripotent-stem-cell-derived human podocytes reconstitute kidney glomerular-capillary-wall function on a chip.
Authors: Authors: Musah S, Mammoto A, Ferrante TC, Jeanty SSF, Hirano-Kobayashi M, Mammoto T, Roberts K, Chung S, Novak R, Ingram M, Fatanat-Didar T, Koshy S, Weaver JC, Church GM, Ingber DE.
Nat Biomed Eng
View full abstract on Pubmed
The whole genome sequences and experimentally phased haplotypes of over 100 personal genomes.
Authors: Authors: Mao Q, Ciotlos S, Zhang RY, Ball MP, Chin R, Carnevali P, Barua N, Nguyen S, Agarwal MR, Clegg T, Connelly A, Vandewege W, Zaranek AW, Estep PW, Church GM, Drmanac R, Peters BA.
Gigascience
View full abstract on Pubmed
Biosensor-based engineering of biosynthetic pathways.
Authors: Authors: Rogers JK, Taylor ND, Church GM.
Curr Opin Biotechnol
View full abstract on Pubmed
Cas9 gRNA engineering for genome editing, activation and repression.
Authors: Authors: Kiani S, Chavez A, Tuttle M, Hall RN, Chari R, Ter-Ovanesyan D, Qian J, Pruitt BW, Beal J, Vora S, Buchthal J, Kowal EJ, Ebrahimkhani MR, Collins JJ, Weiss R, Church G.
Nat Methods
View full abstract on Pubmed
Biocontainment of genetically modified organisms by synthetic protein design.
Authors: Authors: Mandell DJ, Lajoie MJ, Mee MT, Takeuchi R, Kuznetsov G, Norville JE, Gregg CJ, Stoddard BL, Church GM.
Nature
View full abstract on Pubmed
CRISPR/Cas9-Directed Genome Editing of Cultured Cells.
Authors: Authors: Yang L, Yang JL, Byrne S, Pan J, Church GM.
Curr Protoc Mol Biol
View full abstract on Pubmed
Rational optimization of tolC as a powerful dual selectable marker for genome engineering.
Authors: Authors: Gregg CJ, Lajoie MJ, Napolitano MG, Mosberg JA, Goodman DB, Aach J, Isaacs FJ, Church GM.
Nucleic Acids Res
View full abstract on Pubmed
Orthogonal Cas9 proteins for RNA-guided gene regulation and editing.
Authors: Authors: Esvelt KM, Mali P, Braff JL, Moosburner M, Yaung SJ, Church GM.
Nat Methods
View full abstract on Pubmed