Isaac Chiu, PhD

Assistant Professor of Immunology, Harvard Medical School
Silencing Nociceptor Neurons Reduces Allergic Airway Inflammation.
Authors: Authors: Talbot S, Abdulnour RE, Burkett PR, Lee S, Cronin SJ, Pascal MA, Laedermann C, Foster SL, Tran JV, Lai N, Chiu IM, Ghasemlou N, DiBiase M, Roberson D, Von Hehn C, Agac B, Haworth O, Seki H, Penninger JM, Kuchroo VK, Bean BP, Levy BD, Woolf CJ.
Neuron
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Identification of a specific self-reactive IgM antibody that initiates intestinal ischemia/reperfusion injury.
Authors: Authors: Zhang M, Austen WG, Chiu I, Alicot EM, Hung R, Ma M, Verna N, Xu M, Hechtman HB, Moore FD, Carroll MC.
Proc Natl Acad Sci U S A
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Blocking Neuronal Signaling to Immune Cells Treats Streptococcal Invasive Infection.
Authors: Authors: Pinho-Ribeiro FA, Baddal B, Haarsma R, O'Seaghdha M, Yang NJ, Blake KJ, Portley M, Verri WA, Dale JB, Wessels MR, Chiu IM.
Cell
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Correction: Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.
Authors: Authors: Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman G, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf C.
Elife
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MLL 5 protein forms intranuclear foci, and overexpression inhibits cell cycle progression.
Authors: Authors: Deng LW, Chiu I, Strominger JL.
Proc Natl Acad Sci U S A
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Nociceptor sensory neurons suppress neutrophil and ?d T cell responses in bacterial lung infections and lethal pneumonia.
Authors: Authors: Baral P, Umans BD, Li L, Wallrapp A, Bist M, Kirschbaum T, Wei Y, Zhou Y, Kuchroo VK, Burkett PR, Yipp BG, Liberles SD, Chiu IM.
Nat Med
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Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.
Authors: Authors: Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman GS, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf CJ.
Elife
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The human natural killer cell immune synapse.
Authors: Authors: Davis DM, Chiu I, Fassett M, Cohen GB, Mandelboim O, Strominger JL.
Proc Natl Acad Sci U S A
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Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.
Authors: Authors: Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM.
Nat Commun
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Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Authors: Authors: Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ.
Nat Neurosci
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