Isaac Chiu, PhD

Assistant Professor of Immunology, Harvard Medical School
Transcriptional profiling at whole population and single cell levels reveals somatosensory neuron molecular diversity.
Authors: Authors: Chiu IM, Barrett LB, Williams EK, Strochlic DE, Lee S, Weyer AD, Lou S, Bryman GS, Roberson DP, Ghasemlou N, Piccoli C, Ahat E, Wang V, Cobos EJ, Stucky CL, Ma Q, Liberles SD, Woolf CJ.
Elife
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The human natural killer cell immune synapse.
Authors: Authors: Davis DM, Chiu I, Fassett M, Cohen GB, Mandelboim O, Strominger JL.
Proc Natl Acad Sci U S A
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Staphylococcus aureus produces pain through pore-forming toxins and neuronal TRPV1 that is silenced by QX-314.
Authors: Authors: Blake KJ, Baral P, Voisin T, Lubkin A, Pinho-Ribeiro FA, Adams KL, Roberson DP, Ma YC, Otto M, Woolf CJ, Torres VJ, Chiu IM.
Nat Commun
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Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.
Authors: Authors: Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ.
Nat Neurosci
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Trafficking of spontaneously endocytosed MHC proteins.
Authors: Authors: Chiu I, Davis DM, Strominger JL.
Proc Natl Acad Sci U S A
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Erratum: The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation.
Authors: Authors: Wallrapp A, Riesenfeld SJ, Burkett PR, Abdulnour RE, Nyman J, Dionne D, Hofree M, Cuoco MS, Rodman C, Farouq D, Haas BJ, Tickle TL, Trombetta JJ, Baral P, Klose CSN, Mahlakõiv T, Artis D, Rozenblatt-Rosen O, Chiu IM, Levy BD, Kowalczyk MS, Regev A, Kuchroo VK.
Nature
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L-Rhamnose-containing supramolecular nanofibrils as potential immunosuppressive materials.
Authors: Authors: Zhao F, Heesters BA, Chiu I, Gao Y, Shi J, Zhou N, Carroll MC, Xu B.
Org Biomol Chem
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Impaired spontaneous endocytosis of HLA-G.
Authors: Authors: Davis DM, Reyburn HT, Pazmany L, Chiu I, Mandelboim O, Strominger JL.
Eur J Immunol
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Neuro-immune interactions in inflammation and host defense: Implications for transplantation.
Authors: Authors: Chavan SS, Ma P, Chiu IM.
Am J Transplant
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Bacteria activate sensory neurons that modulate pain and inflammation.
Authors: Authors: Chiu IM, Heesters BA, Ghasemlou N, Von Hehn CA, Zhao F, Tran J, Wainger B, Strominger A, Muralidharan S, Horswill AR, Bubeck Wardenburg J, Hwang SW, Carroll MC, Woolf CJ.
Nature
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