James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Molecular genetic analysis of revertants from a poliovirus mutant that is specifically adapted to the mouse spinal cord.
Authors: Authors: Jia Q, Hogle JM, Hashikawa T, Nomoto A.
J Virol
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The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases.
Authors: Authors: Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM.
Proc Natl Acad Sci U S A
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An enzyme-substrate complex involved in bacterial cell wall biosynthesis.
Authors: Authors: Benson TE, Filman DJ, Walsh CT, Hogle JM.
Nat Struct Biol
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Poliovirus chimeras expressing sequences from the principal neutralization domain of human immunodeficiency virus type 1.
Authors: Authors: Dedieu JF, Ronco J, van der Werf S, Hogle JM, Henin Y, Girard M.
J Virol
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The structure of poliovirus.
Authors: Authors: Hogle JM, Chow M, Filman DJ.
Sci Am
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Getting to and through the inner nuclear membrane during herpesvirus nuclear egress.
Authors: Authors: Lye MF, Wilkie AR, Filman DJ, Hogle JM, Coen DM.
Curr Opin Cell Biol
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A 3D framework for understanding enterovirus 71.
Authors: Authors: Hogle JM.
Nat Struct Mol Biol
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Identification of a glycosaminoglycan binding region of the alpha C protein that mediates entry of group B Streptococci into host cells.
Authors: Authors: Baron MJ, Filman DJ, Prophete GA, Hogle JM, Madoff LC.
J Biol Chem
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Functional group placement in protein binding sites: a comparison of GRID and MCSS.
Authors: Authors: Bitetti-Putzer R, Joseph-McCarthy D, Hogle JM, Karplus M.
J Comput Aided Mol Des
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Structure determination of echovirus 1.
Authors: Authors: Filman DJ, Wien MW, Cunningham JA, Bergelson JM, Hogle JM.
Acta Crystallogr D Biol Crystallogr
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