James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Use of MCSS to design small targeted libraries: application to picornavirus ligands.
Authors: Authors: Joseph-McCarthy D, Tsang SK, Filman DJ, Hogle JM, Karplus M.
J Am Chem Soc
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Crystal structure of a 14 bp RNA duplex with non-symmetrical tandem GxU wobble base pairs.
Authors: Authors: Trikha J, Filman DJ, Hogle JM.
Nucleic Acids Res
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The structure of the substrate-free form of MurB, an essential enzyme for the synthesis of bacterial cell walls.
Authors: Authors: Benson TE, Walsh CT, Hogle JM.
Structure
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Virus-ligand structures: the viral canyon.
Authors: Authors: Hogle JM.
Curr Biol
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Myristylation of picornavirus capsid protein VP4 and its structural significance.
Authors: Authors: Chow M, Newman JF, Filman D, Hogle JM, Rowlands DJ, Brown F.
Nature
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Cryo-electron Microscopy Structures of Expanded Poliovirus with VHHs Sample the Conformational Repertoire of the Expanded State.
Authors: Authors: Strauss M, Schotte L, Karunatilaka KS, Filman DJ, Hogle JM.
J Virol
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RNA transfer from poliovirus 135S particles across membranes is mediated by long umbilical connectors.
Authors: Authors: Strauss M, Levy HC, Bostina M, Filman DJ, Hogle JM.
J Virol
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Imaging poliovirus entry in live cells.
Authors: Authors: Brandenburg B, Lee LY, Lakadamyali M, Rust MJ, Zhuang X, Hogle JM.
PLoS Biol
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Molecular genetic analysis of revertants from a poliovirus mutant that is specifically adapted to the mouse spinal cord.
Authors: Authors: Jia Q, Hogle JM, Hashikawa T, Nomoto A.
J Virol
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The enzymological basis for resistance of herpesvirus DNA polymerase mutants to acyclovir: relationship to the structure of alpha-like DNA polymerases.
Authors: Authors: Huang L, Ishii KK, Zuccola H, Gehring AM, Hwang CB, Hogle J, Coen DM.
Proc Natl Acad Sci U S A
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