James Hogle, PhD

Edward S. Harkness Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Use of type 1/type 2 chimeric polioviruses to study determinants of poliovirus type 1 neurovirulence in a mouse model.
Authors: Authors: Martin A, Benichou D, Couderc T, Hogle JM, Wychowski C, Van der Werf S, Girard M.
Virology
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Synthetic peptides from four separate regions of the poliovirus type 1 capsid protein VP1 induce neutralizing antibodies.
Authors: Authors: Chow M, Yabrov R, Bittle J, Hogle J, Baltimore D.
Proc Natl Acad Sci U S A
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Structure of a herpesvirus nuclear egress complex subunit reveals an interaction groove that is essential for viral replication.
Authors: Authors: Leigh KE, Sharma M, Mansueto MS, Boeszoermenyi A, Filman DJ, Hogle JM, Wagner G, Coen DM, Arthanari H.
Proc Natl Acad Sci U S A
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Picornaviruses.
Authors: Authors: Tuthill TJ, Groppelli E, Hogle JM, Rowlands DJ.
Curr Top Microbiol Immunol
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Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
Authors: Authors: Robinson MA, Park S, Sun ZY, Silver PA, Wagner G, Hogle JM.
J Biol Chem
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Computational design of D-peptide inhibitors of hepatitis delta antigen dimerization.
Authors: Authors: Elkin CD, Zuccola HJ, Hogle JM, Joseph-McCarthy D.
J Comput Aided Mol Des
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Ligand-induced conformational changes in poliovirus-antiviral drug complexes.
Authors: Authors: Hiremath CN, Filman DJ, Grant RA, Hogle JM.
Acta Crystallogr D Biol Crystallogr
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Crystallization and preliminary X-ray crystallographic studies of UDP-N-acetylenolpyruvylglucosamine reductase.
Authors: Authors: Benson TE, Walsh CT, Hogle JM.
Protein Sci
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Cell-induced conformational change in poliovirus: externalization of the amino terminus of VP1 is responsible for liposome binding.
Authors: Authors: Fricks CE, Hogle JM.
J Virol
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Divalent cation sites in tomato bushy stunt virus. Difference maps at 2-9 A resolution.
Authors: Authors: Hogle J, Kirchhausen T, Harrison SC.
J Mol Biol
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