John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Construction of cholera toxin B subunit-producing Vibrio cholerae strains using the Mariner-FRT transposon delivery system.
Authors: Authors: Rhie GE, Jung HM, Park J, Kim BS, Mekalanos JJ.
FEMS Immunol Med Microbiol
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An improved technique for isolation of environmental Vibrio cholerae with epidemic potential: monitoring the emergence of a multiple-antibiotic-resistant epidemic strain in Bangladesh.
Authors: Authors: Faruque SM, Islam MJ, Ahmad QS, Biswas K, Faruque AS, Nair GB, Sack RB, Sack DA, Mekalanos JJ.
J Infect Dis
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Genetics of stress adaptation and virulence in toxigenic Vibrio cholerae.
Authors: Authors: Faruque SM, Nair GB, Mekalanos JJ.
DNA Cell Biol
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The human pathogen Pseudomonas aeruginosa utilizes conserved virulence pathways to infect the social amoeba Dictyostelium discoideum.
Authors: Authors: Pukatzki S, Kessin RH, Mekalanos JJ.
Proc Natl Acad Sci U S A
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DNA sequence of both chromosomes of the cholera pathogen Vibrio cholerae.
Authors: Authors: Heidelberg JF, Eisen JA, Nelson WC, Clayton RA, Gwinn ML, Dodson RJ, Haft DH, Hickey EK, Peterson JD, Umayam L, Gill SR, Nelson KE, Read TD, Tettelin H, Richardson D, Ermolaeva MD, Vamathevan J, Bass S, Qin H, Dragoi I, Sellers P, McDonald L, Utterback T, Fleishmann RD, Nierman WC, White O, Salzberg SL, Smith HO, Colwell RR, Mekalanos JJ, Venter JC, Fraser CM.
Nature
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Epidemiology, genetics, and ecology of toxigenic Vibrio cholerae.
Authors: Authors: Faruque SM, Albert MJ, Mekalanos JJ.
Microbiol Mol Biol Rev
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Modulation of horizontal gene transfer in pathogenic bacteria by in vivo signals.
Authors: Authors: Mel SF, Mekalanos JJ.
Cell
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The Vibrio cholerae O139 serogroup antigen includes an O-antigen capsule and lipopolysaccharide virulence determinants.
Authors: Authors: Waldor MK, Colwell R, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Selection for bacterial genes that are specifically induced in host tissues: the hunt for virulence factors.
Authors: Authors: Mahan MJ, Slauch JM, Hanna PC, Camilli A, Tobias JW, Waldor MK, Mekalanos JJ.
Infect Agents Dis
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Regulatory cascade controls virulence in Vibrio cholerae.
Authors: Authors: DiRita VJ, Parsot C, Jander G, Mekalanos JJ.
Proc Natl Acad Sci U S A
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