John Mekalanos, PhD
Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Genetic diversity and virulence potential of environmental Vibrio cholerae population in a cholera-endemic area.
Authors: Authors: Faruque SM, Chowdhury N, Kamruzzaman M, Dziejman M, Rahman MH, Sack DA, Nair GB, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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RS1 element of Vibrio cholerae can propagate horizontally as a filamentous phage exploiting the morphogenesis genes of CTXphi.
Authors: Authors: Faruque SM, Kamruzzaman M, Nandi RK, Ghosh AN, Nair GB, Mekalanos JJ, Sack DA.
Infect Immun
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Infect Immun
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Use of lambda phage S and R gene products in an inducible lysis system for Vibrio cholerae- and Salmonella enterica serovar typhimurium-based DNA vaccine delivery systems.
Induction of the lysogenic phage encoding cholera toxin in naturally occurring strains of toxigenic Vibrio cholerae O1 and O139.
Authors: Authors: Faruque SM, Alim AR, Albert MJ, Islam KM, Mekalanos JJ.
Infect Immun
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Infect Immun
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Alterations in Vibrio cholerae motility phenotypes correlate with changes in virulence factor expression.
Analysis of membrane protein interaction: ToxR can dimerize the amino terminus of phage lambda repressor.
Bacterial response to host signals: analysis and applications.
Periplasmic interaction between two membrane regulatory proteins, ToxR and ToxS, results in signal transduction and transcriptional activation.
Strategies for the development of vaccines for typhoid fever, shigellosis, and cholera.
Nucleotide sequence of the Shiga-like toxin genes of Escherichia coli.
Authors: Authors: Calderwood SB, Auclair F, Donohue-Rolfe A, Keusch GT, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
View full abstract on Pubmed