John Mekalanos, PhD

Adele Lehman Professor of Microbiology and Molecular Genetics, Harvard Medical School
Hyperactive transposase mutants of the Himar1 mariner transposon.
Authors: Authors: Lampe DJ, Akerley BJ, Rubin EJ, Mekalanos JJ, Robertson HM.
Proc Natl Acad Sci U S A
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Neither the Bvg- phase nor the vrg6 locus of Bordetella pertussis is required for respiratory infection in mice.
Authors: Authors: Martinez de Tejada G, Cotter PA, Heininger U, Camilli A, Akerley BJ, Mekalanos JJ, Miller JF.
Infect Immun
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The ToxR protein of Vibrio cholerae forms homodimers and heterodimers.
Authors: Authors: Ottemann KM, Mekalanos JJ.
J Bacteriol
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Vibrio cholerae O139 specific gene sequences.
Authors: Authors: Waldor MK, Mekalanos JJ.
Lancet
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ToxR proteins with substitutions in residues conserved with OmpR fail to activate transcription from the cholera toxin promoter.
Authors: Authors: Ottemann KM, DiRita VJ, Mekalanos JJ.
J Bacteriol
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Expression of ToxR, the transcriptional activator of the virulence factors in Vibrio cholerae, is modulated by the heat shock response.
Authors: Authors: Parsot C, Mekalanos JJ.
Proc Natl Acad Sci U S A
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Characterization of the Vibrio cholerae ToxR regulon: identification of novel genes involved in intestinal colonization.
Authors: Authors: Peterson KM, Mekalanos JJ.
Infect Immun
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Determinants of the immunogenicity of live virulent and mutant Vibrio cholerae O1 in rabbit intestine.
Authors: Authors: Pierce NF, Kaper JB, Mekalanos JJ, Cray WC, Richardson K.
Infect Immun
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Isolation of enterotoxin structural gene deletion mutations in Vibrio cholerae induced by two mutagenic vibriophages.
Authors: Authors: Mekalanos JJ, Moseley SL, Murphy JR, Falkow S.
Proc Natl Acad Sci U S A
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