Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264.
Authors: Authors: Seyedsayamdost MR, Chandler JR, Blodgett JA, Lima PS, Duerkop BA, Oinuma K, Greenberg EP, Clardy J.
Org Lett
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A stabilized demethoxyviridin derivative inhibits PI3 kinase.
Authors: Authors: Yuan H, Pupo MT, Blois J, Smith A, Weissleder R, Clardy J, Josephson L.
Bioorg Med Chem Lett
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A potent dauer pheromone component in Caenorhabditis elegans that acts synergistically with other components.
Authors: Authors: Butcher RA, Ragains JR, Kim E, Clardy J.
Proc Natl Acad Sci U S A
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New antibiotics from bacterial natural products.
Authors: Authors: Clardy J, Fischbach MA, Walsh CT.
Nat Biotechnol
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Coil-to-helix transition and ligand release of Bombyx mori pheromone-binding protein.
Authors: Authors: Lautenschlager C, Leal WS, Clardy J.
Biochem Biophys Res Commun
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Structural and functional analysis of pantocin A: an antibiotic from Pantoea agglomerans discovered by heterologous expression of cloned genes.
Authors: Authors: Jin M, Liu L, Wright SA, Beer SV, Clardy J.
Angew Chem Int Ed Engl
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Pestalone, a new antibiotic produced by a marine fungus in response to bacterial challenge.
Authors: Authors: Cueto M, Jensen PR, Kauffman C, Fenical W, Lobkovsky E, Clardy J.
J Nat Prod
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Cryptocin, a potent tetramic acid antimycotic from the endophytic fungus Cryptosporiopsis cf. quercina.
Authors: Authors: Li JY, Strobel G, Harper J, Lobkovsky E, Clardy J.
Org Lett
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Structures of Cdc42 bound to the active and catalytically compromised forms of Cdc42GAP.
Authors: Authors: Nassar N, Hoffman GR, Manor D, Clardy JC, Cerione RA.
Nat Struct Biol
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Crystallization and preliminary X-ray analysis of twinned crystals of a chimeric FK506 binding protein 12 and 13 complexed with FK506.
Authors: Authors: Liang J, Ealick S, Nielsen C, Schreiber SL, Clardy J.
Acta Crystallogr D Biol Crystallogr
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