Jon Clardy

Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School

Publications

Target identification using drug affinity responsive target stability (DARTS).

Authors: Authors: Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J.
Proc Natl Acad Sci U S A 2009-12-22
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Colorimetric high-throughput screen for detection of heme crystallization inhibitors.

Authors: Authors: Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF.
Antimicrob Agents Chemother 2009-06-01
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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.

Authors: Authors: Mazitschek R, Patel V, Wirth DF, Clardy J.
Bioorg Med Chem Lett 2008-05-01
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Preparation of a psammaplysene-based library.

Authors: Authors: Georgiades SN, Clardy J.
Org Lett 2006-09-14
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Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps.

Authors: Authors: Weibel DB, Lee A, Mayer M, Brady SF, Bruzewicz D, Yang J, Diluzio WR, Clardy J, Whitesides GM.
Langmuir 2005-07-05
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Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

Authors: Authors: Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR.
J Nat Prod 2003-02-01
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Cloning and heterologous expression of a natural product biosynthetic gene cluster from eDNA.

Authors: Authors: Brady SF, Chao CJ, Handelsman J, Clardy J.
Org Lett 2001-06-28
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Structures of human dihydroorotate dehydrogenase in complex with antiproliferative agents.

Authors: Authors: Liu S, Neidhardt EA, Grossman TH, Ocain T, Clardy J.
Structure 2000-01-15
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Chorismate mutase-prephenate dehydratase from Escherichia coli. Study of catalytic and regulatory domains using genetically engineered proteins.

Authors: Authors: Zhang S, Pohnert G, Kongsaeree P, Wilson DB, Clardy J, Ganem B.
J Biol Chem 1998-03-13
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New insight into the catalytic mechanism of chorismate mutases from structural studies.

Authors: Authors: Lee AY, Stewart JD, Clardy J, Ganem B.
Chem Biol 1995-04-01
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