Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Synthesis and antiplasmodial activity of novel 2,4-diaminopyrimidines.
Authors: Authors: Martyn DC, Nijjar A, Celatka CA, Mazitschek R, Cortese JF, Tyndall E, Liu H, Fitzgerald MM, O'Shea TJ, Danthi S, Clardy J.
Bioorg Med Chem Lett
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Thirteen posttranslational modifications convert a 14-residue peptide into the antibiotic thiocillin.
Authors: Authors: Wieland Brown LC, Acker MG, Clardy J, Walsh CT, Fischbach MA.
Proc Natl Acad Sci U S A
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Bombyx mori pheromone-binding protein binding nonpheromone ligands: implications for pheromone recognition.
Authors: Authors: Lautenschlager C, Leal WS, Clardy J.
Structure
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A biosynthetic gene cluster for the acetyl-CoA carboxylase inhibitor andrimid.
Authors: Authors: Jin M, Fischbach MA, Clardy J.
J Am Chem Soc
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Long-chain N-acyltyrosine synthases from environmental DNA.
Authors: Authors: Brady SF, Chao CJ, Clardy J.
Appl Environ Microbiol
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Structures and cytotoxic properties of sponge-derived bisannulated acridines.
Authors: Authors: Thale Z, Johnson T, Tenney K, Wenzel PJ, Lobkovsky E, Clardy J, Media J, Pietraszkiewicz H, Valeriote FA, Crews P.
J Org Chem
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The cytosporones, new octaketide antibiotics isolated from an endophytic fungus.
Authors: Authors: Brady SF, Wagenaar MM, Singh MP, Janso JE, Clardy J.
Org Lett
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Chiral resolution and stereospecificity of 6-phenyl-4-phenylethynyl- 1,4-dihydropyridines as selective A(3) adenosine receptor antagonists.
Authors: Authors: Jiang J, Li AH, Jang SY, Chang L, Melman N, Moro S, Ji X, Lobkovsky EB, Clardy JC, Jacobson KA.
J Med Chem
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Antifungal diterpenoid alkaloids from Delphinium denudatum.
Authors: Authors: Nasreen A, Akhtar F, Shekhani MS, Clardy J, Parvez M, Choudhary MI.
J Nat Prod
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Atomic structure of the trypsin-A90720A complex: a unified approach to structure and function.
Authors: Authors: Lee AY, Smitka TA, Bonjouklian R, Clardy J.
Chem Biol
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