Jon Clardy, PhD
Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Closing in on a new treatment for sleeping sickness.
Mixing and matching siderophore clusters: structure and biosynthesis of serratiochelins from Serratia sp. V4.
Authors: Authors: Seyedsayamdost MR, Cleto S, Carr G, Vlamakis H, João Vieira M, Kolter R, Clardy J.
J Am Chem Soc
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J Am Chem Soc
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Dihydrophenylalanine: a prephenate-derived Photorhabdus luminescens antibiotic and intermediate in dihydrostilbene biosynthesis.
Authors: Authors: Crawford JM, Mahlstedt SA, Malcolmson SJ, Clardy J, Walsh CT.
Chem Biol
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Chem Biol
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Targeted discovery of polycyclic tetramate macrolactams from an environmental Streptomyces strain.
Target identification using drug affinity responsive target stability (DARTS).
Authors: Authors: Lomenick B, Hao R, Jonai N, Chin RM, Aghajan M, Warburton S, Wang J, Wu RP, Gomez F, Loo JA, Wohlschlegel JA, Vondriska TM, Pelletier J, Herschman HR, Clardy J, Clarke CF, Huang J.
Proc Natl Acad Sci U S A
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Proc Natl Acad Sci U S A
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Colorimetric high-throughput screen for detection of heme crystallization inhibitors.
Authors: Authors: Rush MA, Baniecki ML, Mazitschek R, Cortese JF, Wiegand R, Clardy J, Wirth DF.
Antimicrob Agents Chemother
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Antimicrob Agents Chemother
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Development of a fluorescence polarization based assay for histone deacetylase ligand discovery.
Authors: Authors: Mazitschek R, Patel V, Wirth DF, Clardy J.
Bioorg Med Chem Lett
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Bioorg Med Chem Lett
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Preparation of a psammaplysene-based library.
Bacterial printing press that regenerates its ink: contact-printing bacteria using hydrogel stamps.
Authors: Authors: Weibel DB, Lee A, Mayer M, Brady SF, Bruzewicz D, Yang J, Diluzio WR, Clardy J, Whitesides GM.
Langmuir
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Langmuir
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Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.
Authors: Authors: Amagata T, Whitman S, Johnson TA, Stessman CC, Loo CP, Lobkovsky E, Clardy J, Crews P, Holman TR.
J Nat Prod
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J Nat Prod
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