Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Diversity-oriented synthesis yields novel multistage antimalarial inhibitors.
Authors: Authors: Kato N, Comer E, Sakata-Kato T, Sharma A, Sharma M, Maetani M, Bastien J, Brancucci NM, Bittker JA, Corey V, Clarke D, Derbyshire ER, Dornan GL, Duffy S, Eckley S, Itoe MA, Koolen KM, Lewis TA, Lui PS, Lukens AK, Lund E, March S, Meibalan E, Meier BC, McPhail JA, Mitasev B, Moss EL, Sayes M, Van Gessel Y, Wawer MJ, Yoshinaga T, Zeeman AM, Avery VM, Bhatia SN, Burke JE, Catteruccia F, Clardy JC, Clemons PA, Dechering KJ, Duvall JR, Foley MA, Gusovsky F, Kocken CH, Marti M, Morningstar ML, Munoz B, Neafsey DE, Sharma A, Winzeler EA, Wirth DF, Scherer CA, Schreiber SL.
Nature
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Variable genetic architectures produce virtually identical molecules in bacterial symbionts of fungus-growing ants.
Authors: Authors: Sit CS, Ruzzini AC, Van Arnam EB, Ramadhar TR, Currie CR, Clardy J.
Proc Natl Acad Sci U S A
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Cellulolytic Streptomyces strains associated with herbivorous insects share a phylogenetically linked capacity to degrade lignocellulose.
Authors: Authors: Book AJ, Lewin GR, McDonald BR, Takasuka TE, Doering DT, Adams AS, Blodgett JA, Clardy J, Raffa KF, Fox BG, Currie CR.
Appl Environ Microbiol
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1,2,3,4,6-Penta-O-galloyl-ß-D-glucopyranose inhibits angiogenesis via inhibition of capillary morphogenesis gene 2.
Authors: Authors: Cryan LM, Bazinet L, Habeshian KA, Cao S, Clardy J, Christensen KA, Rogers MS.
J Med Chem
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Microtermolides A and B from termite-associated Streptomyces sp. and structural revision of vinylamycin.
Authors: Authors: Carr G, Poulsen M, Klassen JL, Hou Y, Wyche TP, Bugni TS, Currie CR, Clardy J.
Org Lett
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Sources of diversity in bactobolin biosynthesis by Burkholderia thailandensis E264.
Authors: Authors: Carr G, Seyedsayamdost MR, Chandler JR, Greenberg EP, Clardy J.
Org Lett
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Psychrotrophic strain of Janthinobacterium lividum from a cold Alaskan soil produces prodigiosin.
Authors: Authors: Schloss PD, Allen HK, Klimowicz AK, Mlot C, Gross JA, Savengsuksa S, McEllin J, Clardy J, Ruess RW, Handelsman J.
DNA Cell Biol
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Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans.
Authors: Authors: Kim K, Sato K, Shibuya M, Zeiger DM, Butcher RA, Ragains JR, Clardy J, Touhara K, Sengupta P.
Science
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Induction of apoptosis in endometrial cancer cells by psammaplysene A involves FOXO1.
Authors: Authors: Berry E, Hardt JL, Clardy J, Lurain JR, Kim JJ.
Gynecol Oncol
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High-throughput screens for small-molecule inhibitors of Pseudomonas aeruginosa biofilm development.
Authors: Authors: Junker LM, Clardy J.
Antimicrob Agents Chemother
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