Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Minimum Information about a Biosynthetic Gene cluster.
Authors: Authors: Medema MH, Kottmann R, Yilmaz P, Cummings M, Biggins JB, Blin K, de Bruijn I, Chooi YH, Claesen J, Coates RC, Cruz-Morales P, Duddela S, Düsterhus S, Edwards DJ, Fewer DP, Garg N, Geiger C, Gomez-Escribano JP, Greule A, Hadjithomas M, Haines AS, Helfrich EJ, Hillwig ML, Ishida K, Jones AC, Jones CS, Jungmann K, Kegler C, Kim HU, Kötter P, Krug D, Masschelein J, Melnik AV, Mantovani SM, Monroe EA, Moore M, Moss N, Nützmann HW, Pan G, Pati A, Petras D, Reen FJ, Rosconi F, Rui Z, Tian Z, Tobias NJ, Tsunematsu Y, Wiemann P, Wyckoff E, Yan X, Yim G, Yu F, Xie Y, Aigle B, Apel AK, Balibar CJ, Balskus EP, Barona-Gómez F, Bechthold A, Bode HB, Borriss R, Brady SF, Brakhage AA, Caffrey P, Cheng YQ, Clardy J, Cox RJ, De Mot R, Donadio S, Donia MS, van der Donk WA, Dorrestein PC, Doyle S, Driessen AJ, Ehling-Schulz M, Entian KD, Fischbach MA, Gerwick L, Gerwick WH, Gross H, Gust B, Hertweck C, Höfte M, Jensen SE, Ju J, Katz L, Kaysser L, Klassen JL, Keller NP, Kormanec J, Kuipers OP, Kuzuyama T, Kyrpides NC, Kwon HJ, Lautru S, Lavigne R, Lee CY, Linquan B, Liu X, Liu W, Luzhetskyy A, Mahmud T, Mast Y, Méndez C, Metsä-Ketelä M, Micklefield J, Mitchell DA, Moore BS, Moreira LM, Müller R, Neilan BA, Nett M, Nielsen J, O'Gara F, Oikawa H, Osbourn A, Osburne MS, Ostash B, Payne SM, Pernodet JL, Petricek M, Piel J, Ploux O, Raaijmakers JM, Salas JA, Schmitt EK, Scott B, Seipke RF, Shen B, Sherman DH, Sivonen K, Smanski MJ, Sosio M, Stegmann E, Süssmuth RD, Tahlan K, Thomas CM, Tang Y, Truman AW, Viaud M, Walton JD, Walsh CT, Weber T, van Wezel GP, Wilkinson B, Willey JM, Wohlleben W, Wright GD, Ziemert N, Zhang C, Zotchev SB, Breitling R, Takano E, Glöckner FO.
Nat Chem Biol
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Insights into secondary metabolism from a global analysis of prokaryotic biosynthetic gene clusters.
Authors: Authors: Cimermancic P, Medema MH, Claesen J, Kurita K, Wieland Brown LC, Mavrommatis K, Pati A, Godfrey PA, Koehrsen M, Clardy J, Birren BW, Takano E, Sali A, Linington RG, Fischbach MA.
Cell
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Synthesis and activity of biomimetic biofilm disruptors.
Authors: Authors: Böttcher T, Kolodkin-Gal I, Kolter R, Losick R, Clardy J.
J Am Chem Soc
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Liver-stage malaria parasites vulnerable to diverse chemical scaffolds.
Authors: Authors: Derbyshire ER, Prudêncio M, Mota MM, Clardy J.
Proc Natl Acad Sci U S A
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Bacterial symbionts and natural products.
Authors: Authors: Crawford JM, Clardy J.
Chem Commun (Camb)
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Exploiting a global regulator for small molecule discovery in Photorhabdus luminescens.
Authors: Authors: Kontnik R, Crawford JM, Clardy J.
ACS Chem Biol
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D-amino acids govern stationary phase cell wall remodeling in bacteria.
Authors: Authors: Lam H, Oh DC, Cava F, Takacs CN, Clardy J, de Pedro MA, Waldor MK.
Science
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Type II NADH dehydrogenase of the respiratory chain of Plasmodium falciparum and its inhibitors.
Authors: Authors: Dong CK, Patel V, Yang JC, Dvorin JD, Duraisingh MT, Clardy J, Wirth DF.
Bioorg Med Chem Lett
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One pathway, many products.
Authors: Authors: Fischbach MA, Clardy J.
Nat Chem Biol
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Isolation and structure assignment of an iminotetrasaccharide from a cultured filamentous cyanobacterium Anabaena sp.
Authors: Authors: Thammana S, Suzuki H, Lobkovsky E, Clardy J, Shimizu Y.
J Nat Prod
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