Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis.
Authors: Authors: Bellizzi JJ, Widom J, Kemp C, Lu JY, Das AK, Hofmann SL, Clardy J.
Proc Natl Acad Sci U S A
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Megathyrin B: a cytotoxic diterpene from Isodon megathyrsus.
Authors: Authors: Qiu SX, Sun HD, Lobkovsky E, Chai H, Clardy J, Farnsworth NR, Pezzuto JM, Fong HH.
Planta Med
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Structure of the spiroketal-macrolide ossamycin.
Authors: Authors: Kirst HA, Mynderse JS, Martin JW, Baker PJ, Paschal JW, Rios Steiner JL, Lobkovsky E, Clardy J.
J Antibiot (Tokyo)
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Atomic structure of FKBP-FK506, an immunophilin-immunosuppressant complex.
Authors: Authors: Van Duyne GD, Standaert RF, Karplus PA, Schreiber SL, Clardy J.
Science
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Bipolaroxin, a selective phytotoxin produced by Bipolaris cynodontis.
Authors: Authors: Sugawara F, Strobel G, Fisher LE, Van Duyne GD, Clardy J.
Proc Natl Acad Sci U S A
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Letter: The structure of saxitoxin.
Authors: Authors: Schantz EJ, Ghazarossian VE, Schnoes HK, Strong FM, Springer JP, Pezzanite JO, Clardy J.
J Am Chem Soc
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Burkholderia from Fungus Gardens of Fungus-Growing Ants Produces Antifungals That Inhibit the Specialized Parasite Escovopsis.
Authors: Authors: Francoeur CB, May DS, Thairu MW, Hoang DQ, Panthofer O, Bugni TS, Pupo MT, Clardy J, Pinto-Tomás AA, Currie CR.
Appl Environ Microbiol
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Pyonitrins A-D: Chimeric Natural Products Produced by Pseudomonas protegens.
Authors: Authors: Mevers E, Saurí J, Helfrich EJN, Henke M, Barns KJ, Bugni TS, Andes D, Currie CR, Clardy J.
J Am Chem Soc
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Pyrazines from bacteria and ants: convergent chemistry within an ecological niche.
Authors: Authors: Silva-Junior EA, Ruzzini AC, Paludo CR, Nascimento FS, Currie CR, Clardy J, Pupo MT.
Sci Rep
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Discovery of Reactive Microbiota-Derived Metabolites that Inhibit Host Proteases.
Authors: Authors: Guo CJ, Chang FY, Wyche TP, Backus KM, Acker TM, Funabashi M, Taketani M, Donia MS, Nayfach S, Pollard KS, Craik CS, Cravatt BF, Clardy J, Voigt CA, Fischbach MA.
Cell
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