Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
A self-produced trigger for biofilm disassembly that targets exopolysaccharide.
Authors: Authors: Kolodkin-Gal I, Cao S, Chai L, Böttcher T, Kolter R, Clardy J, Losick R.
Cell
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Aminoindoles, a novel scaffold with potent activity against Plasmodium falciparum.
Authors: Authors: Barker RH, Urgaonkar S, Mazitschek R, Celatka C, Skerlj R, Cortese JF, Tyndall E, Liu H, Cromwell M, Sidhu AB, Guerrero-Bravo JE, Crespo-Llado KN, Serrano AE, Lin JW, Janse CJ, Khan SM, Duraisingh M, Coleman BI, Angulo-Barturen I, Jiménez-Díaz MB, Magán N, Gomez V, Ferrer S, Martínez MS, Wittlin S, Papastogiannidis P, O'Shea T, Klinger JD, Bree M, Lee E, Levine M, Wiegand RC, Munoz B, Wirth DF, Clardy J, Bathurst I, Sybertz E.
Antimicrob Agents Chemother
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D-amino acids trigger biofilm disassembly.
Authors: Authors: Kolodkin-Gal I, Romero D, Cao S, Clardy J, Kolter R, Losick R.
Science
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An indole-containing dauer pheromone component with unusual dauer inhibitory activity at higher concentrations.
Authors: Authors: Butcher RA, Ragains JR, Clardy J.
Org Lett
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Actin-aggregating cucurbitacins from Physocarpus capitatus.
Authors: Authors: Maloney KN, Fujita M, Eggert US, Schroeder FC, Field CM, Mitchison TJ, Clardy J.
J Nat Prod
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Small-molecule pheromones that control dauer development in Caenorhabditis elegans.
Authors: Authors: Butcher RA, Fujita M, Schroeder FC, Clardy J.
Nat Chem Biol
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Stopping trouble before it starts.
Authors: Authors: Clardy J.
ACS Chem Biol
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A further study of the cytotoxic constituents of a milnamide-producing sponge.
Authors: Authors: Sonnenschein RN, Farias JJ, Tenney K, Mooberry SL, Lobkovsky E, Clardy J, Crews P.
Org Lett
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Ceriopsin E, a new epoxy ent-kaurene diterpenoid from Ceriops decandra.
Authors: Authors: Anjaneyulu AS, Rao VL, Lobkovsky E, Clardy J.
J Nat Prod
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Rhizobium etli CE3 carries vir gene homologs on a self-transmissible plasmid.
Authors: Authors: Bittinger MA, Gross JA, Widom J, Clardy J, Handelsman J.
Mol Plant Microbe Interact
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