Jon Clardy, PhD

Hsien Wu and Daisy Yen Wu Professor of Biological Chemistry and Molecular Pharmacology, Harvard Medical School
Macrotermycins A-D, Glycosylated Macrolactams from a Termite-Associated Amycolatopsis sp. M39.
Authors: Authors: Beemelmanns C, Ramadhar TR, Kim KH, Klassen JL, Cao S, Wyche TP, Hou Y, Poulsen M, Bugni TS, Currie CR, Clardy J.
Org Lett
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A New Diketopiperazine, Cyclo(D-trans-Hyp-L-Leu) from a Kenyan Bacterium Bacillus licheniformis LB 8CT.
Authors: Authors: Lee SR, Beemelmanns C, Tsuma LM, Clardy J, Cao S, Kim KH.
Nat Prod Commun
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The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs.
Authors: Authors: Herman JD, Pepper LR, Cortese JF, Estiu G, Galinsky K, Zuzarte-Luis V, Derbyshire ER, Ribacke U, Lukens AK, Santos SA, Patel V, Clish CB, Sullivan WJ, Zhou H, Bopp SE, Schimmel P, Lindquist S, Clardy J, Mota MM, Keller TL, Whitman M, Wiest O, Wirth DF, Mazitschek R.
Sci Transl Med
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Natural products and synthetic biology.
Authors: Authors: Seyedsayamdost MR, Clardy J.
ACS Synth Biol
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Catecholate siderophores protect bacteria from pyochelin toxicity.
Authors: Authors: Adler C, Corbalán NS, Seyedsayamdost MR, Pomares MF, de Cristóbal RE, Clardy J, Kolter R, Vincent PA.
PLoS One
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A high-throughput screen identifies a new natural product with broad-spectrum antibacterial activity.
Authors: Authors: Ymele-Leki P, Cao S, Sharp J, Lambert KG, McAdam AJ, Husson RN, Tamayo G, Clardy J, Watnick PI.
PLoS One
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The selectivity of austocystin D arises from cell-line-specific drug activation by cytochrome P450 enzymes.
Authors: Authors: Marks KM, Park ES, Arefolov A, Russo K, Ishihara K, Ring JE, Clardy J, Clarke AS, Pelish HE.
J Nat Prod
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Chemical modification of the insecticidal briantheins X and Y.
Authors: Authors: Cronan JM, Lee A, Liang J, Clardy J, Cardellina JH.
J Nat Prod
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The natural history of antibiotics.
Authors: Authors: Clardy J, Fischbach MA, Currie CR.
Curr Biol
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FOXO3a mediates the cytotoxic effects of cisplatin in colon cancer cells.
Authors: Authors: Fernández de Mattos S, Villalonga P, Clardy J, Lam EW.

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